Braunodin B. Brown ointment 10%, 250 g

An antiseptic agent which is a complex of iodine and povidone, effective at pH from 2 to 7. Bactericidal effect is due to free active iodine, which is released from the povidone-iodine complex.

In comparison with alcohol-containing iodine solutions, aqueous solution of povidone iodine has a significantly lower irritant effect.

Indications

– post-traumatic and postoperative wounds of various localization, burns, trophic ulcers, bedsores, diabetic foot;

– skin injuries of various origin, maceration, abrasions, contusions. Skin infections of various etiologies including infectious dermatitis and eczema;

– treatment of patient’s mucous membranes and skin before and after operations, biopsies, punctures, including skin around drainage, catheters and probes;

– hygienic treatment of medical personnel hands, surgical hands treatment;

– infections of the oral cavity and nasopharynx;

– infections of the mucosa of the birth canal in women;

– performing “small” gynecological operations (artificial termination of pregnancy, IUD insertion, coagulation of erosion and polyp).

Active ingredient

Composition

100 g of the solution contain:

the active ingredient:

povidone iodine (with 10% active iodine content) 7.5 g;

auxiliary substances:

Sodium dihydrophosphate dihydrate,

Lauromacrogol-400,

sodium iodate,

sodium hydroxide,

purified water up to 100 g.

Interaction

The drug is incompatible with alkaloid salts (celandine), tannic acid (tannin), salicylic acid, salts of silver, bismuth, taurolidine and hydrogen peroxide.

In the presence of blood and pus the drug binds to proteins and other organic compounds, as a result of which its bactericidal activity may be reduced. In this case it is recommended to increase the multiplicity/frequency of administration of the drug.

The simultaneous use of povidone iodine and topical products containing enzymes may contribute to oxidation and inhibition of their enzymatic activity.

Povidone iodine synergizes with lithium preparations, and therefore reversible suppression of thyroid function may occur with prolonged use. Therefore, patients who regularly take lithium preparations should avoid prolonged application of povidone iodine on large surfaces.

The drug may lead to false-positive results in some diagnostic tests: determination of hemoglobin or sugar in urine and stool, thyroid function tests. Examination of the thyroid gland in this case should be carried out not earlier than 1-2 weeks after the end of treatment with povidone-iodine.

Directions for use

Externally, topically.

The drug is used as a 7.5% solution or diluted. For dilution of the drug can be used 0.9% sodium chloride solution, Ringer’s solution, phosphate buffer solution.

Povidone iodine is applied to the surface by dabbing with a swab dipped in the solution, by irrigation with a mechanical sprayer, and also by leaving napkins soaked in the solution on the surface.

The drug in the form of 7.5% solution is used for antiseptic treatment of shallow wounds, burns, skin lesions: abrasions, bruises; for treatment of skin and mucous membranes of the patient before and after surgery, biopsy or puncture, skin around drains, catheters and probes.

When treating the skin prior to surgery, the solution should be used, avoiding “pooling” it under the patient as this can cause skin irritation.

To treat the hands of surgical personnel, 5 ml of the product in a 7.5% solution is applied to the hands and treated for 2.5 minutes. The procedure is repeated twice. For hygienic treatment of hands apply 3 ml to the skin and treat for 1 minute. Then they are rinsed off thoroughly with water.

The drug in diluted form is used:

– in dilution 1:2 – 1:20 to wash deep wounds, bedsores, trophic ulcers, for intraoperative wound care;

– in dilution 1:25 for preoperative preparation of patients: limb washing;

– in dilution 1:100 in preoperative preparation of patients: body washing;

– as 1% solution when diluted with phosphate buffer solution: application to the mucous membrane of the eyes.

All solutions of the drug shall be used only freshly prepared.

Povidone iodine solutions should be applied to the damaged surface until it is completely moist.

Towel cloths soaked in povidone iodine solution should be applied to the wound sutures. The antiseptic film formed when povidone-iodine dries is easily washed off with water.

The use of povidone iodine solutions should continue until signs of infection have disappeared or there is no apparent risk of infection.

Povidone iodine solutions are not irritating and do not slow down wound healing, even with prolonged use.

Special Instructions

Features

Contraindications

– Hypersensitivity to the drug components.

– Thyroid disorders (thyrotoxicosis).

– Thyroid adenoma.

– Duhring’s dermatitis herpetiformis.

– Concurrent use of radioactive iodine.

– Premature infants, newborns and children under 6 months.

Chronic renal failure.

Side effects

Possible hypersensitivity reactions to the drug: Delayed-type allergic reactions (itching, redness of skin, blisters) or immediate-type allergic reactions (anaphylactoid reactions).

. Long use of the drug (more than 7-10 days) and application on large surfaces of skin, large wounds due to absorption may lead to iodine phenomena (“metallic” taste in the mouth, increased salivation and lacrimation, mucous membrane edema) and system reactions (metabolic acidosis, hyponatremia, renal and thyroid disorders), if they occur, the drug use should be stopped and a doctor should be consulted.

Overdose

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