Bisacodyl-Nizhpharm, rectal 10 mg 10 pcs

Causes irritation of the receptor apparatus of the intestine, has a direct effect on the intestinal mucosa, increasing its peristalsis and increasing mucus secretion in the large intestine.

It is not absorbed in the intestine. It is a prodrug; in an alkaline environment hydrolysis occurs with the formation of a metabolite which has an irritating effect on the mucous membrane of the gastrointestinal tract. The action occurs within the first hour.

Indications

Constipation caused by hypotension and sluggish peristalsis of the colon (particularly in elderly patients; constipation after surgery, childbirth). Regulating stool for hemorrhoids, proctitis, anal fissures.

Preparation for surgical operations, instrumental and x-ray examinations.

Pharmacological effect

Causes irritation of the intestinal receptor apparatus, has a direct effect on the intestinal mucosa, enhancing its peristalsis and increasing the secretion of mucus in the large intestine.

Not absorbed in the intestines. It is a prodrug; hydrolysis occurs in an alkaline environment to form a metabolite, which has an irritating effect on the mucous membrane of the gastrointestinal tract. The action occurs within the first hour.

Special instructions

Bisacodyl should not be used for long-term treatment of chronic constipation.

Active ingredient

Bisacodyl

Composition

One suppository contains:

Active ingredient:

Bisacodyl – 10 mg

Suppository base:

Solid fat (Vitepsol, brands H15, W35, Supposir, brands NA 15, NAS 50) – until a suppository weighing 1.25 g is obtained.

Pregnancy

The drug should be used with caution in pregnant and lactating women.

Contraindications

Hypersensitivity, intestinal obstruction, strangulated hernia, acute inflammatory diseases of the abdominal organs, peritonitis, bleeding from the gastrointestinal tract, metrorrhagia, cystitis, spastic constipation, acute proctitis, acute hemorrhoids, children under 8 years of age.

With caution

Liver and/or renal failure.

Side Effects

Allergic reactions, rectal irritation, intestinal colic, diarrhea, which can lead to excessive loss of fluid and electrolytes and, consequently, to the development of muscle weakness, cramps, hypotension.

Overdose

Symptoms: diarrhea, dehydration, water-electrolyte imbalance, hypokalemia, colon atony.

Treatment: symptomatic.

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

2 years. Do not use the drug after the expiration date.

Manufacturer

Nizhpharm JSC, Russia