Betahistin-Vertex, tablets 8 mg 30 pcs

Betahistine acts mainly on histamine H1- and H3-receptors of the inner ear and vestibular nuclei of the CNS. By direct agonist effect on H]-receptors of the inner ear vessels, as well as indirectly through the effect on Hz-receptors, it improves microcirculation and capillary permeability, normalizes the endolymph pressure in the labyrinth and cochlea. At the same time, betahistine increases blood flow in the basilar artery.

It has a pronounced central effect, being an inhibitor of Hz-receptor nuclei of the vestibular nerve. It improves conduction in neurons of vestibular nuclei at brainstem level.

The clinical manifestation of the above properties is reduction of the frequency and intensity of dizziness, reduction of tinnitus, improvement of hearing if it is reduced.

Indications

treatment and prevention of vestibular vertigo of various origins
syndromes including dizziness and headache, tinnitus, progressive hearing loss, nausea and vomiting
Meniere’s disease or syndrome.

Pharmacological effect

Betahistine acts mainly on histamine H1 and H3 receptors in the inner ear and vestibular nuclei of the central nervous system. By direct agonistic effect on H]-receptors of the vessels of the inner ear. and also indirectly, through its effect on H3 receptors, improves microcirculation and capillary permeability, normalizes endolymph pressure in the labyrinth and cochlea. At the same time, betahistine increases blood flow in the basilar artery.

It has a pronounced central effect, being an inhibitor of H3 receptors in the nuclei of the vestibular nerve. Improves conductivity in neurons of the vestibular nuclei at the level of the brain stem.

The clinical manifestation of these properties is a decrease in the frequency and intensity of dizziness, a decrease in tinnitus, and an improvement in hearing if it is reduced.

Special instructions

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Active ingredient

Betahistine

Composition

active substance:

betahistine dihydrochloride – 8 mg

excipients:

microcrystalline cellulose – 6.64 mg,

lactose monohydrate – 40 mg,

citric acid monohydrate – 2.5 mg,

colloidal silicon dioxide – 3.75 mg,

talc – 3.1 mg,

calcium stearate – 1.25 mg;

Pregnancy

There is insufficient data to assess the effects of the drug during pregnancy and lactation.

In this regard, use during pregnancy is not recommended. During treatment it is necessary to stop breastfeeding.

Contraindications

Hypersensitivity to any of the components of the drug – children under 18 years of age (due to lack of data).

With caution

Peptic ulcer of the gastrointestinal tract (including a history), pheochromocytoma. bronchial asthma. These patients should be monitored regularly during treatment.

Side Effects

“”>Tablets 8 mg:

Overdose

2 tablets 3 times a day.

Improvement is usually noted already at the beginning of therapy, a stable therapeutic effect occurs after two weeks of treatment and can increase over several months of treatment. The treatment is long-term. The duration of taking the drug is selected individually.

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Storage conditions

Gastrointestinal disorders, the appearance of hypersensitivity reactions on the skin (rash, itching, urticaria), Quincke’s edema.

Manufacturer

Vertex, Russia