Berokka Plus, orange-flavored effervescent tablets 30 pcs

Indications

Deficiency or conditions accompanied by an increased need for B vitamins, vitamin C and zinc.

Composition

Tablets effervescent flat-cylindrical, pale orange to light orange in color, with flecks of darker and lighter colors; they dissolve in water with the release of bubbles, forming a solution with a smell of orange.

1 tablet contains:

ascorbic acid (Vit. C)500 mg

Thiamine hydrochloride (Vit. B1)115 mg

Riboflavin (Vit. B2)215 mg

Pantothenic acid (Vit. B5)323 mg

Pyridoxine hydrochloride (Vit. B6)10 mg

Folium acid (Vit. Bc)400 µg

Cyanocobalamin (Vit. B12)410 µg

Nicotinamide (Vit. B3)50 mg

Biotin (Vit. B8)150 µg

calcium (in the form of calcium carbonate and calcium pantothenate)5100 mg

magnesium (in the form of magnesium carbonate heavy and magnesium sulfate dihydrate)6100 mg

Zinc (in the form of zinc trihydrate)710 mg.

Auxiliary substances: citric acid anhydrous – 1700 mg,

sodium bicarbonate – 840 mg,

anhydrous sodium carbonate – 60 mg,

sodium chloride – 40 mg,

acetulfame potassium – 20 mg,

aspartame – 25 mg,

beet red (E162) – 30 mg,

beta carotene (E160a) – 40 mg,

orange flavoring – 100 mg,

polysorbate 60 – 900 µg,

mannitol – 16.848 mg,

isomalt – 265.531 mg,

sorbitol – 155.3027 mg.

How to take, the dosage

1 tablet a day.

The effervescent tablets should be dissolved in a glass of water.

The recommended duration of treatment is 30 days.

Interaction

Pyridoxine at a dose greater than 5 mg may neutralize the effects of levodopa in patients with parkinsonism. However, this antagonism is not observed when levodopa is used in combination with a decarboxylase inhibitor (e.g., benserazide, cardbidopa).

Thiosemicarbazone and 5-fluorouracil neutralize the effects of thiamine.

The antacid drugs inhibit thiamine resorption.

Neomycin, aminosalicylic acid and histamine H2-receptor blockers reduce absorption of cyanocobalamin.

Acetylsalicylic acid reduces absorption of ascorbic acid by approximately one third.

The oral contraceptives may decrease serum levels of cyanocobalamin, folic acid, pyridoxine, and ascorbic acid.

In some patients taking deferoxamine and ascorbic acid at a dose of 500 mg daily, transient left ventricular dysfunction may be noted.

Special Instructions

If there is intolerance to some sugars, consult a physician before taking the drug.

Patients taking other medications should consult a physician before taking the drug.

The recommended daily dose of the drug should not be exceeded.

The effervescent tablet contains 272 mg of sodium, and film-coated tablets are recommended for patients on a low-salt diet.

Synopsis

Contraindications

– hypersensitivity to the components of the drug,

– hypercalcemia,

– hypermagnesemia,

– urolithiasis (nephrolithiasis, urolithiasis),

– hemochromatosis,

– hyperoxaluria,

– impaired renal function,

– glucose-6-phosphate dehydrogenase deficiency,

– fructose intolerance,

– under 15 years of age.

With caution: in atrophic gastritis, intestinal diseases, pancreatic diseases, vitamin B12 malabsorption syndrome.

Overdose

No cases of overdose have been reported.

Symptoms:Gastrointestinal disorders such as diarrhea and a feeling of discomfort in the stomach area may occur. Excessive intake of vitamin B6 (more than 20 tablets/day and for several months) may lead to symptoms of neuropathy.

Treatment:The patient should stop taking the drug and see a doctor.