Antitumor agent. It is a selective non-steroidal aromatase inhibitor. In postmenopause estradiol is mainly formed from estrone, which is produced in peripheral tissues by conversion from androstenedione (with the participation of aromatase enzyme). Reducing circulating estradiol levels has a therapeutic effect in women with breast cancer. In postmenopause, anastrozole at a daily dose of 1 mg causes a decrease in estradiol levels by 80%. Anastrozole has no progestogenic, androgenic and estrogenic activity; in therapeutic doses it does not affect cortisol and aldosterone secretion.
Pharmacokinetics
Indications
Active ingredient
Composition
White, round, biconvex, film-coated tablets with “ANA 1” engraved on one side of the tablet; white or almost white on the fracture.
Associates:
Lactose monohydrate,
povidone,
sodium carboxymethyl starch,
magnesium stearate.
Film coating:
Opadray white (macrogol 400, hypromellose, titanium dioxide).
How to take, the dosage
Interaction
Special Instructions
Contraindications
Side effects
Weight | 0.013 kg |
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Manufacturer | Sinton Spain S.L., Spain |
Medication form | pills |
Brand | Sinton Spain S.L. |
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