Allochol, 10 pcs.

Pharmacotherapeutic group

Holeretic drug

ATX code: A05AX

Pharmacodynamics:

The diuretic (cholekinetic and choleretic) reduces the processes of putrefaction and fermentation in the intestine. Enhances secretory function of liver cells reflexively increases secretory and motor activity of the organs of the gastrointestinal tract. Increases the formation of bile and bile acids.

The action of bile is conditioned by its reflexive influence on the secretory function of the liver parenchyma. Bile also enhances secretory and motor functions of the gastrointestinal tract.

The substances in garlic increase secretory and motor function of the gastrointestinal tract and stimulate the secretion of bile.

The nettle leaves have choleretic and anti-inflammatory properties.

The activated charcoal is an adsorbent that binds toxic substances in the gastrointestinal tract.

Pharmacokinetics:

The drug is well absorbed in the gastrointestinal tract. Cholic and chenodeoxycholic acids contained in the drug are subjected to 7-alpha-dehydroxylation in the intestine. Moreover, cholic acid undergoes metabolism in the liver: it conjugates with amino acids and is secreted into the bile, from where it is again excreted into the intestine and then partially reabsorbed; the rest is excreted through the intestine.

Indications

Biliary dyskinesia, Hepatitis, Constipation, Cholecystitis, PainCronic hepatitis, cholangitis, cholecystitis, atonic constipation.

Active ingredient

Activated charcoal, Bile, Nettle leaves, Garlic bulbs

Composition

Composition per tablet:

Bovine bile – 80 mg

Garlic seed bulbs – 40 mg

Cornerbark leaves – 5 mg

Activated charcoal – 25 mg.

Excipients:

core: potato starch – 34.25 mg, magnesium oxide – 10.25 mg, talc – 5.25 mg, colloidal silicon dioxide (aerosil) – 8.25 mg, calcium stearate – 2.00 mg;

shell:

. VIVACOAT PM-2P-050 – 21.00 mg [hypromellose (hydroxy propyl methylcellulose) (E 464) – 10.500 mg, titanium dioxide – 5.540 mg, talc – 2.100 mg, macrogol-3350 (polyethylene glycol-3350) – 1.050 mg, Hyprolose (hydroxypropyl cellulose) – 1.050 mg, sunset yellow dye (E 110) – 0.025 mg, quinoline yellow dye (E 104) – 0.430 mg, iron oxide yellow dye (E 172) – 0.305 mg];

OPADRY II 85F19250 Clear – 2.00 mg [polyvinyl alcohol – 1.045 mg, macrogol (polyethylene glycol) – 0.295 mg, talc – 0.600 mg, polysorbate-80 (tween-80) – 0.060 mg].

How to take, the dosage

Internal, after meals, 1-2 tablets 3-4 times a day, for 3-4 weeks.

In case of exacerbation 1 tablet 2-3 times a day for 1 – 2 months.

Children over 7 years old – 1 tablet 3 times a day for 3 – 4 weeks.

Interaction

Drugs containing aluminum hydroxide, colestyramine, colestipol reduce absorption and reduce the effect of the drug. Simultaneous use is not advisable.

Synopsis

Filmed film-coated tablets are light yellow to yellow, round, biconvex. The cross section is grayish-black in color, light-colored blotches are allowed.

Contraindications

Hypersensitivity, calculous cholecystitis, obstructive jaundice, acute hepatitis, acute and subacute liver dystrophy, peptic ulcer and duodenal ulcer, acute pancreatitis.

Children under 7 years (for this dosage form).

Side effects

Diarrhea, allergic reactions.

Pregnancy use

With caution: Pregnancy, lactation.