Alfinal, tablets 5 mg, 30 pcs.

Alfinal is an anti-tumor hormonal drug. It inhibits 5-alpha reductase, which converts testosterone into more active 5-alpha-dihydrotestosterone, reduces its concentration in blood and prostate tissue within 24 hours after oral administration.

Indications

Active ingredient

Composition

1 tablet contains:

Active substance:

finasteride 5 mg

Associates:

Lactose monohydrate,

Microcrystalline cellulose,

How to take, the dosage

Interaction

No clinically significant interactions of finasteride with propranolol, digoxin, glyburide, warfarin, theophylline and antipyrine have been found.

Apparently, finasteride has no significant effect on the cytochrome P450 enzyme system and, accordingly, does not affect the pharmacokinetic parameters of drugs metabolized by liver microsomal enzymes.

When using finasteride concomitantly with ACE inhibitors, alpha-adrenoblockers, beta-adrenoblockers, calcium channel blockers, nitrates, diuretics, histamine H

Special Instructions

In patients with a large volume of residual urine and/or sharply reduced urine flow, the possible development of obstructive uropathy should be closely monitored.

Before initiating therapy, diseases stimulating benign prostatic hyperplasia, such as prostate cancer, urethral stricture, bladder hypotension, bladder innervation disorders, and infectious prostatitis should be excluded.

Women of childbearing age and pregnant women should avoid contact with the drug (especially touching crushed or broken tablets) because the drug has teratogenic properties (its ability to inhibit the conversion of testosterone to dihydrotestosterone can cause abnormal genital development in the male fetus) and penetrates the seminal fluid.

Causes a decrease in PSA after 6 and 12 months of use by 41% and 48%, respectively. Patients should be evaluated to rule out the development of prostate cancer during therapy with Alfinal®.

If a dose of Alfinal® is missed, we recommend continuing treatment as usual. Excessive doses of the drug should not be taken.

Contraindications

Side effects

Overdose

Similarities