Alburex 20%, 50 ml
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Human albumin makes up more than half of the protein fraction of human blood plasma and about 10% of the protein synthesized by the liver.
Physicochemical properties: human albumin with a dosage of 200 g/l has hyperoncotic effect. The most important physiological functions of albumin are its contribution to blood oncotic pressure and transport functions.
Restoration and maintenance of circulating blood volume in case of its deficiency with the expediency of using colloidal solutions.
How to take, the dosage
Albumin concentration, dosing regimen and infusion rate of the infusion solution should be selected individually for each patient.
The interaction of human albumin with other medicinal products has not been established.
Alburex® must not be mixed with other medicinal products (except for isotonic solutions, e.g. dextrose 5% solution or sodium chloride 0.9% solution), whole blood and red blood cell mass.
Albumin solutions must not be diluted with water for injection, as this may cause hemolysis in recipients.
Hypersensitivity to the active ingredient or any other component of the drug.
The adverse reactions presented below are listed according to organ and organ system involvement (MedDRA classification) and frequency of occurrence. The frequency is defined as follows: very common (≥1/10), common (≥1/100 and < 1/10), infrequent (≥1/1,000 and < 1/100), rare (≥1/10,000 and < 1/1,000), very rare (< 1/10,000, including individual cases). Frequency categories were formed based on clinical studies of the drug and post-registration surveillance.
Mild reactions such as blood “flushes,” urticaria, fever, and nausea are rare. These reactions usually disappear quickly when the drug is reduced or discontinued. Very rarely, severe reactions such as shock may occur. In these cases, the drug administration should be stopped immediately and appropriate treatment initiated.
Hypervolemia may develop if the dose or rate of administration is high.
At the first clinical signs of cardiovascular overload (headache, dyspnea, jugular vein swelling) or elevated blood pressure, central venous pressure and pulmonary edema, the infusion should be stopped immediately and continuous hemodynamic monitoring should be performed.
The safety of Alburex® administration during pregnancy has not been established in controlled clinical trials. However, clinical experience with Alburex® does not suggest any harmful effects on pregnancy, the fetus or the newborn.
|Conditions of storage|
At the temperature not more than 30 ° C in the light-protected place. Do not freeze. Keep out of reach of children.
CSEL Bering AG, Switzerland
solution for infusion
CSEL Bering AG
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