Alburex 20%, 50 ml

Human albumin makes up more than half of the protein fraction of human blood plasma and about 10% of the protein synthesized by the liver.
Physicochemical properties: human albumin with a dosage of 200 g/l has hyperoncotic effect. The most important physiological functions of albumin are its contribution to blood oncotic pressure and transport functions.

Indications

Traumatic and postoperative shock, burns accompanied by dehydration and blood concentration, hypoproteinemia and hypoalbuminemia, developing with nutritional dystrophy, nephrotic syndromes, glomerulonephritis, cirrhosis of the liver, prolonged purulent processes, damage to the gastrointestinal tract with malnutrition of the patient (including peptic ulcer, tumors).

Pharmacological effect

Clinical and pharmacological group: Plasma replacement drug. Human albumin preparation

Pharmacotherapeutic group: Plasma replacement agent

Pharmacological action

A product obtained by fractionating blood, plasma, placenta, serum from healthy donors. Maintains colloid-osmotic (oncotic) blood pressure, increases blood volume, and increases blood pressure. Promotes the penetration of tissue fluid into the bloodstream. Is a source of protein.

Special instructions

Patients with dehydration should ensure sufficient fluid intake before administering human albumin.

Use with caution in patients with reduced cardiac reserve due to an increased risk of developing acute heart failure.

When using drugs from human blood and plasma, the possibility of infection with infectious diseases cannot be completely excluded.

Use during pregnancy and breastfeeding

During pregnancy, the use of human albumin is possible only in cases of extreme necessity.

There are no data on the safety of human albumin during lactation.

Use for liver dysfunction

Possible use depending on the clinical situation.

Use for renal dysfunction

Possible use depending on the clinical situation.

Use in children

Possible use depending on the clinical situation.

Use in elderly patients

Use with caution in elderly patients due to the risk of overloading the cardiovascular system.

Active ingredient

Human albumin

Composition

Active substance: human albumin

Excipients: sodium acetyltryptophan – 16 mmol, sodium caprylate – 16 mmol, sodium chloride – up to sodium content 140 mmol, water for injection – up to 1 liter.

Pregnancy

During pregnancy, the use of human albumin is possible only in cases of extreme necessity.

Contraindications

Thrombosis, arterial hypertension, ongoing internal bleeding, severe anemia, severe forms of heart failure, hypersensitivity to human albumin.

Side Effects

From the digestive system: possible nausea, vomiting, hypersalivation.

From the cardiovascular system: arterial hypotension, tachycardia.

Allergic reactions: possible urticaria; rarely – anaphylactic shock.

Other: possible increase in body temperature, pain in the lumbar region.

Interaction

With simultaneous use of human albumin with ACE inhibitors, the risk of developing arterial hypotension increases.

Manufacturer

CSL Behring AG, Switzerland