Albumin, 10% 100 ml

How to take, the dosage

Albumin solution 10% is administered intravenously by drip or stream.

The single dose of the drug depends on the concentration of albumin solution, initial condition and age of the patient. Albumin solutions of 10% are administered in a dose of 200-300 ml.

The rate of administration of 10% albumin solution is not more than 40 drops per minute.

Jet infusion of albumin solutions is acceptable in shocks of various genesis for rapid increase in blood pressure.

In pediatric practice the dosage of albumin solutions is calculated taking into account the concentration in milliliters per kilogram of body weight (not more than 3 ml/kg of child’s body weight).

Interaction

The simultaneous use of albumin with ACE inhibitors increases the risk of arterial hypotension.

Special Instructions

Before using the drug, the doctor registers the label data (drug name, manufacturing company, series number) in the patient’s medical history.

In the elderly, rapid administration of 10% albumin solution should be avoided, as it may lead to cardiovascular overload.

Albumin solutions should be warmed to room temperature before starting the infusion. The drug is not suitable for use in containers with compromised integrity or labeling, with changes in physical properties (color changes, clouding of the solution, the presence of suspended solids, sediment), with expired shelf life, improper storage.

Contraindications

• Hypersensitivity.
• Severe forms of heart failure (due to possible acute heart failure).
• Thrombosis.
• Severe forms of arterial hypertension.
• Continued internal bleeding.
• Hypervolemia.
• Pulmonary edema.
• Severe anemia.
• Cerebral edema.

With caution when: renal failure, bronchial asthma, allergic rhinitis, Quincke’s edema.

Side effects

Injection of albumin 10% solution, as a rule, is not accompanied by adverse reactions and complications, sometimes it is possible to develop:

• Allergic reactions of varying severity (urticaria and others).
• Hyperthermia.
• Pain in the lumbar region.
  

Overdose

In case of overdose or too rapid administration of the drug the phenomenon of hypervolemia may occur (development of pulmonary edema, increased arterial and central venous pressure).

In case of initial signs of anaphylactic reaction or signs of overdose (headache, shortness of breath, suffocation) albumin transfusion should be stopped immediately and without removing the needle from the vein the appropriate drugs (glucocorticosteroids, vasopressor drugs if indicated) should be injected.

Pregnancy use

In pregnancy, the use of human albumin is possible only in cases of extreme necessity.