Uro-Gial pH 6, 5-7.5, 50 ml

Hyaluronic acid, is a high molecular weight glycosaminoglycan, which consists of repeating disaccharides N-acetylglucosamine and glucuronic acid.

Hyaluronic acid is a constituent of all body tissues and is the most significant component of the intercellular matrix and forms a significant proportion of glycosaminoglycans of the urothelium of the bladder and urethra (urinary tract).

The medical product Uro-Gial is a viscoelastic protector of the intercellular substance of the urothelium of the bladder and urethra.

Injected into the bladder cavity it creates a viscoelastic film on the surface of the mucous membrane protecting it from external factors with various manipulations (urethroscopy, cystoscopy, prostate and bladder TUR, pelvic radiotherapy etc.).

Indications

Temporary protection of the mucous membrane of the bladder during various types of manipulations (urethro-cystoscopy, radiation therapy, etc.). In addition, numerous scientific studies have proven the effectiveness of using sodium hyaluronate for the following diseases:

Chronic/recurrent cystitis;
Radiation cystitis;
Interstitial cystitis;
Overactive bladder (as part of complex therapy with M-anticholinergics or vanilloid receptor agonists (RTX))

Pharmacological effect

Hyaluronic acid is a high molecular weight glycosaminoglycan, which consists of repeating disaccharides N-acetylglucosamine and glucuronic acid.

Hyaluronic acid is part of all tissues of the body and is the most significant component of the intercellular matrix and constitutes a significant proportion of glycosaminoglycans in the urothelium of the bladder and urethra (urethra).

The medical drug Uro-Gyal is a viscoelastic protector of the intercellular substance of the urothelium of the bladder and urethra.

When introduced into the cavity of the bladder, it creates a viscoelastic film on the surface of the mucous membrane, protecting it from external influences during various types of manipulations (urethroscopy, cystoscopy, TUR of the prostate and bladder, radiation therapy of the pelvic organs, etc.).

Special instructions

The drug Uro-Gyal is intended only for introduction into the bladder cavity using a urological catheter.

Exudate the injection, strictly observing the rules of asepsis.

Before use, check the integrity and tightness of the bottle: do not use the drug if the bottle or its cap is damaged, and also check the integrity of the packaging of the syringe, needle and urological catheter. If they are damaged, the use of the drug is not permissible.

Do not use after expiration date.

Uro-Gyal is intended for instillation into the bladder, which must be performed by a doctor with special training in a specially equipped room, in compliance with all rules of asepsis.

Composition

1 ml of solution contains:

sodium hyaluronate 0.8 mg,

sodium dihydrogen phosphate monohydrate 0.45 mg,

disodium phosphate anhydrous 2 mg,

sodium chloride 8.5 mg±0.05,

deionized water q.s.

Contraindications

Hypersensitivity to one of the components of the Uro-Gial composition,
Pregnancy,
breastfeeding,
children.

Side Effects

No side effects were identified.

Individual intolerance may occur.

Interaction

Incompatibility has been noted between sodium hyaluronate and quaternary ammonium salts such as benzalkonium chloride.

Uro-Gyal should not come into contact with such drugs or with medical and surgical instruments treated with such drugs.

Storage conditions

Store at temperatures between +5 °C and +25 °C.

Manufacturer

SLS, Russia