Thiamine, 50 µg/ml 1 ml 10 pcs

Thiamine influences the conduction of nerve excitation in synapses, has ganglioblocking and curare-like properties. It is of great importance for the function of the nervous system, the digestive system, cardiac activity, and the endocrine system.

The source of thiamine for humans is food. In the absence or insufficient intake with food or with various conditions that prevent its absorption and assimilation, a person develops symptoms of hypo- and avitaminosis B1.

B1 avitaminosis, called beri- beri, runs either with paralysis and exhaustion or with heart damage and edema.

Indications

Hypovitaminosis and B1 avitaminosis, including in patients on probe feeding, hemodialysis, with malabsorption syndrome.

. As part of the complex therapy – neuritis and polyneuritis, radiculitis, neuralgia, peripheral paresis and paralysis, Wernicke’s encephalopathy, psychosis Korsakov, chronic liver damage, various intoxications, myocardiodystrophy, coronary circulation disorders, gastric and 12 duodenal ulcer, atonic constipation, atony of the bowel; Dermatoses (eczema, atopic dermatitis, psoriasis, lichen planus) with neurotrophic changes and metabolic disorders; thyrotoxicosis, diabetes, endarteritis; pyoderma.

Composition

How to take, the dosage

Intramuscularly (deep into the muscle).

Start parenteral administration with low doses (not more than 0.5 ml of 5 or 2.5% solution) and only if tolerated, administer higher doses.

Adults are prescribed 0.02-0.05 g of thiamine chloride (1 ml of 2.5 or 5% solution) once a day, daily; children are administered 0.0125 g (0.5 ml of 2.5% solution) of thiamine chloride. The course of treatment is 10 to 30 injections.

Interaction

Thiamine chloride solution should not be mixed with solutions containing sulfites, since it is completely disintegrated in them.

Parenteral administration of thiamine with pyridoxine or cyanocobalamin is not recommended: pyridoxine hinders the conversion of thiamine into its biologically active form, cyanocobalamin increases the allergic effect of thiamine.

Thiamine and penicillin or streptomycin should not be mixed in the same syringe (destruction of antibiotics), thiamine and nicotinic acid (destruction of thiamine).

Limits the effect of depolarizing myorelaxants (suxamethonium iodide, etc.).

Special Instructions

Parenteral administration is recommended only if oral administration is not possible (nausea, vomiting, malabsorption syndrome, preoperative or postoperative conditions).

In Wernicke’s encephalopathy the administration of dextrose should precede the administration of thiamine.

Contraindications

Hypersensitivity.