Terginan, vaginal tablets 6 pcs

Combination drug for topical application in gynecology. It has antimicrobial, anti-inflammatory, antiprotozoal, antifungal effects; it ensures the integrity of the vaginal mucosa and pH constancy.

Ternidazole is an antifungal agent of the group of imidazole derivatives, reduces the synthesis of ergosterol (a component of the cell membrane), changes the structure and properties of the cell membrane. It has trichomonacidal effect, it is also active against anaerobic bacteria, in particular gardnerella.

Neomycin is a broad-spectrum antibiotic of the aminoglycoside group. It is bactericidal against Gram-positive (Staphylococcus, Streptococcus pneumoniae) and Gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; against Streptococcus spp.

Resistance of microorganisms develops slowly and to a small extent.

Nistatin is an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi of the genus Candida, it changes the permeability of cell membranes and slows their growth.

Prednisolone is a dehydrated analog of hydrocortisone with pronounced anti-inflammatory, anti-allergic and anti-exudative action.

Indications

Treatment of vaginitis caused by microorganisms sensitive to the drug, including:

bacterial vaginitis;
vaginal trichomoniasis;
vaginitis caused by fungi of the genus Candida;
mixed vaginitis.

Prevention of vaginitis, including:

before gynecological operations;
before childbirth and abortion;
before and after installation of intrauterine devices;
before and after diathermocoagulation of the cervix;
before hysterography.

Pharmacological effect

Combined drug for local use in gynecology. Has antimicrobial, anti-inflammatory, antiprotozoal, antifungal effects; ensures the integrity of the vaginal mucosa and pH constancy.

Ternidazole is an antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (a component of the cell membrane), changes the structure and properties of the cell membrane. It has a trichomonacid effect and is also active against anaerobic bacteria, in particular gardnerella.

Neomycin is a broad-spectrum antibiotic from the aminoglycoside group. It has a bactericidal effect against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; against Streptococcus spp., inactive.

Microbial resistance develops slowly and to a small extent.

Nystatin is an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.

Prednisolone is a dehydrated analogue of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.

Special instructions

It is necessary to simultaneously treat the sexual partner due to the risk of re-infection.

Active ingredient

Neomycin, Nystatin, Prednisolone, Ternidazole

Composition

Active ingredients:

ternidazole – 0.2 g,

neomycin sulfate – 0.1 g or 65,000 IU,

nystatin – 100,000 IU,

prednisolone sodium metasulfobenzoate – 0.0047 g,

equivalent to prednisolone – 0.003 g.

Excipients:

wheat starch – 0.264 g,

lactose monohydrate – q.s. up to 1.2 g,

colloidal silicon dioxide – 0.006 g,

magnesium stearate – 0.01 g,

sodium carboxymethyl starch – 0.048 g.

Pregnancy

It is possible to use Terzhinan during pregnancy and lactation (breastfeeding) according to indications.

Contraindications

Hypersensitivity to the components of the drug.

Side Effects

Burning sensation, itching and irritation in the vagina (especially at the beginning of treatment).

In some cases, allergic reactions are possible.

Overdose

Due to the low degree of absorption into the systemic circulation, an overdose is unlikely.

Storage conditions

Store at room temperature.

Shelf life

See packaging.

Manufacturer

Sofartex, France