Tantum Verde, tablets 3 mg 20 pcs

Pharmacotherapeutic group: nonsteroidal anti-inflammatory drug

ATX code: A01AD02

Pharmacological properties

Pharmacodynamics

Benzidamine is a non-steroidal anti-inflammatory drug, belongs to the group of indazoles. It has anti-inflammatory and local analgesic effect, has antiseptic action against a wide range of microorganisms.

The mechanism of action of the drug is associated with stabilization of cell membranes and inhibition of prostaglandin synthesis.

Benzidamine has antibacterial and specific antimicrobial action due to rapid penetration through the membranes of microorganisms with subsequent damage of cell structures, disruption of metabolic processes and cell lysosomes.

It has antifungal action against Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzidamine in inflammatory processes in the oral cavity, including infectious etiology.

Pharmacokinetics

When used topically, the drug is well absorbed through mucous membranes and penetrates inflamed tissues, being detected in blood plasma in amounts insufficient to produce systemic effects.Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products.

Indications

Active ingredient

Composition

In one tablet to be taken in a mouthful:

Active ingredient – benzidamine hydrochloride – 3mg.

Auxiliary Ingredients:

Isomaltose 3183 mg,

Racementol 4 mg,

aspartame 3.5 mg,

citric acid,

monohydrate 2 mg,

mint flavoring 5 mg,

lemon flavoring 1.5 mg,

quinoline yellow dye (E104) 0.035 mg,

indigo carmine dye (E132) 0.015 mg.

How to take, the dosage

Topically, after meals. Adults (including elderly patients) and children over 6 years: 1 tablet for dissolution 3 times a day. The tablets are kept in the mouth until they are completely dissolved.

Do not swallow. Do not chew. Do not exceed the recommended dose. Children from 6 to 12 years of age should use the drug under the supervision of an adult.

The duration of treatment should not exceed 7 days. If after 7 days of treatment there is no improvement or new symptoms appear, a physician should be consulted.

Please only use the drug according to the route of administration and in the doses mentioned in the instructions. If necessary, please talk to your doctor before using this medicine.

Interaction

There have been no studies of interaction with other medicinal products.

Special Instructions

Hypersensitivity reactions may occur during use of Tantum® Verde. In this case, it is recommended to discontinue treatment and consult a physician for appropriate therapy.

In a limited number of patients, the presence of ulcers in the throat and mouth may indicate more serious disease. If symptoms persist for more than 3 days, you should consult a physician.

The use of Tantum® Verde is not recommended in patients who are hypersensitive to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.

Tantum® Verde should be used with caution in patients with a history of bronchial asthma because of the possibility of bronchospasm associated with the drug.

The drug contains isomaltose and therefore it is not recommended in patients with hereditary fructose intolerance.

The drug can only be used in children under adult supervision to avoid swallowing the tablet.

Impact on the ability to drive vehicles and operate machinery

It does not affect the ability to drive vehicles and operate machinery.

Contraindications

– hypersensitivity to benzidamine or other components of the drug;

– fructose intolerance;

– children under 6 years of age;

– phenylketonuria

With caution

High sensitivity to acetylsalicylic acid or other nonsteroidal anti-inflammatory drugs, bronchial asthma (including anamnesis.including in anamnesis).

Side effects

World Health Organization (WHO) Classification of the frequency of side effects:

very common – ≥1/10;

frequent – ≥1/100 to infrequent – ≥1/1000 to rare – ≥1/10000 to very rare – frequency unknown – cannot be estimated based on available data.In each group, adverse effects are presented in decreasing order of severity.

Local reactions: rare – dry mouth, burning sensation in the oral cavity; frequency unknown – feeling of numbness in the oral cavity.

Allergic reactions: infrequent – photosensitization; rare – hypersensitivity reactions. skin rash, itching; very rare – angioedema, laryngospasm; frequency unknown – anaphylactic reactions.

If any of the side effects listed in the instructions worsen, or any other side effects not listed in the instructions are noted, the doctor should be informed immediately.

Overdose

Tantum® Verde has not currently been reported as an overdose.

Symptoms: If the drug is used according to the instructions for use, overdose is unlikely. If the drug is accidentally swallowed, the following symptoms may occur: vomiting, abdominal cramps, restlessness, fear, hallucinations, seizures, ataxia, fever, tachycardia, respiratory depression.

Treatment: symptomatic; empty stomach by inducing vomiting or gastric lavage, using a gastric tube (under medical supervision); provide medical supervision, supportive therapy, and adequate hydration. An antidote is not known.

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