Tantum Verde, tablets 3 mg 20 pcs
€13.84 €11.53
Pharmacotherapeutic group: nonsteroidal anti-inflammatory drug
ATX code: A01AD02
Pharmacological properties
Pharmacodynamics
Benzidamine is a non-steroidal anti-inflammatory drug, belongs to the group of indazoles. It has anti-inflammatory and local analgesic effect, has antiseptic action against a wide range of microorganisms.
The mechanism of action of the drug is associated with stabilization of cell membranes and inhibition of prostaglandin synthesis.
Benzidamine has antibacterial and specific antimicrobial action due to rapid penetration through the membranes of microorganisms with subsequent damage of cell structures, disruption of metabolic processes and cell lysosomes.
It has antifungal action against Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzidamine in inflammatory processes in the oral cavity, including infectious etiology.
Pharmacokinetics
When used topically, the drug is well absorbed through mucous membranes and penetrates inflamed tissues, being detected in blood plasma in amounts insufficient to produce systemic effects.Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products.
Indications
Symptomatic treatment of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies):
gingivitis, glossitis, stomatitis (including after radiation and chemotherapy);
pharyngitis, laryngitis, tonsillitis;
candidiasis of the oral mucosa (as part of combination therapy);
calculous inflammation of the salivary glands;
condition after surgical interventions and injuries (tonsillectomy, jaw fractures);
condition after treatment and tooth extraction;
periodontal disease.
For infectious and inflammatory diseases requiring systemic treatment, it is necessary to use Tantum® Verde as part of combination therapy.
Pharmacological effect
Pharmacotherapeutic group: non-steroidal anti-inflammatory drug
ATX code: A01AD02
Pharmacological properties
Pharmacodynamics
Benzidamine is a non-steroidal anti-inflammatory drug that belongs to the indazoles group. It has an anti-inflammatory and local analgesic effect, and has an antiseptic effect against a wide range of microorganisms.
The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.
Benzidamine has an antibacterial and specific antimicrobial effect due to rapid penetration through the membranes of microorganisms with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes.
Has antifungal effect against Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzydamine for inflammatory processes in the oral cavity, including infectious etiology.
Pharmacokinetics
When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues; it is found in the blood plasma in quantities insufficient to obtain systemic effects. Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products.
Special instructions
When using the drug Tantum® Verde, hypersensitivity reactions may develop. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy.
In a limited number of patients, the presence of ulcers in the throat and mouth may indicate a more serious condition. If symptoms persist for more than 3 days, you should consult your doctor.
The use of Tantum® Verde is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
The drug Tantum® Verde should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm in them while taking the drug.
The drug contains isomaltose and, therefore, is not recommended for patients with hereditary fructose intolerance.
The use of the drug in children is possible only under adult supervision to avoid swallowing the tablet.
Impact on the ability to drive vehicles and machinery
Does not affect the ability to drive vehicles and operate machinery.
Active ingredient
Benzydamine
Composition
For one lozenge:
Active ingredient – benzydamine hydrochloride – 3 mg.
Auxiliary ingredients:
isomaltose 3183 mg,
racementol 4 mg,
aspartame 3.5 mg,
citric acid,
monohydrate 2 mg,
mint flavor 5 mg,
lemon flavor 1.5 mg,
quinoline yellow dye (E104) 0.035 mg,
indigo carmine dye (E132) 0.015 mg.
Contraindications
– hypersensitivity to benzydamine or other components of the drug;
– fructose intolerance;
– children under 6 years of age;
– phenylketonuria
With caution
Hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including a history).
Side Effects
World Health Organization (WHO) side effect frequency classification:
very often – ≥1/10;
common – ≥ 1/100 to uncommon – ≥ 1/1000 to rare – ≥ 1/10,000 to very rare – frequency unknown – cannot be estimated from available data. In each group, adverse effects are presented in order of decreasing severity.
Local reactions: rarely – dry mouth, burning sensation in the oral cavity; frequency unknown – feeling of numbness in the oral cavity.
Allergic reactions: uncommon – photosensitivity; rarely – hypersensitivity reactions. skin rash, skin itching; very rarely – angioedema, laryngospasm; frequency unknown – anaphylactic reactions.
If any of the side effects indicated in the instructions worsen, or any other side effects not listed in the instructions are noted, you should immediately inform your doctor.
Interaction
No interaction studies have been conducted with other drugs.
Overdose
Currently, no cases of overdose of Tantum® Verde have been reported.
Symptoms: when using the drug in accordance with the instructions for use, an overdose is unlikely. If the drug is accidentally ingested, the following symptoms are possible: vomiting, abdominal cramps, anxiety, fear, hallucinations, convulsions, ataxia, fever, tachycardia, respiratory depression.
Treatment: symptomatic; cleanse the stomach by inducing vomiting or flushing the stomach using a gastric tube (under medical supervision); provide medical supervision, supportive care and necessary hydration. No antidote is known.
Storage conditions
In a place protected from light, at a temperature not exceeding 25 °C
Shelf life
4 years.
Do not use after expiration date.
Manufacturer
Aziende Chimique Riunite Angelini Francesco A.C.R.A., Italy
Shelf life | 4 years. Do not use after the expiration date. |
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Conditions of storage | In a light-protected place, at a temperature not exceeding 25 °C |
Manufacturer | Asiende Chimica Riunita Angelini Francesco A.C.R.A., Italy |
Medication form | lozenges |
Brand | Asiende Chimica Riunita Angelini Francesco A.C.R.A. |
Other forms…
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