Sulfacyl sodium, eye drops 20% 1.5 ml 2 pcs

Antimicrobial bacteriostatic agent, sulfonamide.

The mechanism of action is due to competitive antagonism with para-aminobenzoic acid, inhibition of dihydropteroate synthetase, disruption of tetrahydrofolic acid synthesis, required for purine and pyrimidine synthesis.

• Active against Gram-positive and phamotropic cocci:
  • Escherichia coli.
  • Shigella spp.
  • Vibrio cholerae.
  • Clostridium perfringens.
  • Bacillus anthracis.
  • Cory nebacleri urn diphthcriae.
  • Yersinia pestis.
  • Chlamydia spp.
  • Actinomyces israelii.
  • Toxoplasma gondii.

Pharmacokinetics

In local administration, penetrates tissues and fluids of the eye. It may penetrate into the systemic bloodstream through the inflamed conjunctiva, but due to the small amount of the drug, no systemic effect is determined.

Indications

Conjunctivitis.
Blepharitis.
Purulent ulcer of the cornea.
Prevention and treatment of blenorrhea in newborns.
Gonorrheal and chlamydial eye diseases in adults.

Pharmacological effect

Antimicrobial bacteriostatic agent, sulfanilamide.

The mechanism of action is due to competitive antagonism with para-aminobenzoic acid, inhibition of dihydropteroate synthetase, disruption of the synthesis of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidines.

Active against gram-positive and phamo-negative cocci:
Escherichia coli.
Shigella spp.
Vibrio cholerae.
Clostridium perfringens.
Bacillus anthracis.
Cory nebacleri urn diphthcriae.
Yersinia pestis.
Chlamydia spp.
Actinomyces israelii.
Toxoplasma gondii.

Pharmacokinetics

When applied topically, it penetrates into the tissues and fluids of the eye. It can penetrate into the systemic bloodstream through the inflamed conjunctiva, however, due to the small amount of the drug, the systemic effect is not determined.

Special instructions

Patients with increased individual sensitivity to furosemide, thiazide diuretics, sulfonylureas or carbonhydrase inhibitors may exhibit increased sensitivity to sodium sulfacyl.

Prescribe with caution to patients with a history of allergies.

Active ingredient

Sulfacetamide

Composition

1 ml eye drops contains:

active ingredient:

sodium sulfacetamide monohydrate (sodium sulfacetamide), calculated as 100% substance 200 mg,

excipients:

sodium thiosulfate – 1 mg;

hydrochloric acid solution 1 M – to pH 8;

water for injection – up to 1 ml

Contraindications

Increased individual sensitivity to sulfonamide drugs.

Side Effects

When using the drug, local tissue irritation (burning, redness, swelling, pain, lacrimation) and allergic reactions are possible.

Interaction

Combined use with novocaine and dicaine reduces the bacteriostatic effect of sodium sulfacyl.

Incompatibility of sodium sulfacyl is observed when used in combination with silver salts.

Storage conditions

In a place protected from light, at a temperature of 8–15 °C.

Shelf life

2 years

Manufacturer

Moscow Endocrine Plant, Russia