Structum, capsules 0,5 g 60 pcs

Structum affects metabolic processes in hyaline and fibrous cartilage, reduces degenerative processes in the cartilage of joints, stimulates the biosynthesis of glycosaminglycans. It slows down bone tissue resorption and decreases calcium loss, accelerates the bone tissue repair processes. Application of Structum reduces pain and improves mobility of affected joints. The therapeutic effect is maintained for a long time after the end of the course of therapy.

Pharmacokinetics

Intake and distribution

After oral administration more than 70% of chondroitin sulfate is absorbed from the GI tract. After a single use in an average therapeutic dose Cmax in plasma is reached after 3-4 hours, in the synovial fluid – after 4-5 hours. Bioavailability of the drug is 13%. Chondroitin sulfate accumulates in synovial fluid.

Elimination

Extracted by the kidneys.

Indications

Active ingredient

Composition

1 capsule contains:

The active ingredient:

chondroitin sulfate sodium 500 mg

Associates:

talc 10 mg

Capsule shell (body and cap) composition:

How to take, the dosage

Ingestion with water.

Adults and adolescents from 15 years of age – 1 g/day: 2 capsules (250 mg) or 1 capsule (500 mg) 2 times a day.

The recommended duration of the initial course is 6 months; the period of action of the drug after discontinuation is 3-5 months depending on the location and stage of the disease; the duration of repeated courses is determined by the doctor.

Interaction

The simultaneous use of the drug Structum may increase the effect of indirect anticoagulants, antiaggregants and fibrinolytic agents.

Special Instructions

With caution, the drug is prescribed in case of bleeding or a tendency to bleeding.

Contraindications

Pregnancy; lactation (breastfeeding).

Side effects

Rarely: allergic reactions, nausea, diarrhea.

Pregnancy use

It is not recommended due to insufficient clinical data.

Similarities