Sodium chloride 0.9%, 400 ml

Sodium and chlorine ions are the most important inorganic components of extracellular fluid.

They maintain the appropriate osmotic pressure of blood plasma and extracellular fluid.

In case of dehydration, isotonic solution replenishes fluid deficit in the body.

Hypertensive sodium chloride solution when administered by IV provides correction of the osmotic pressure of extracellular fluid and blood plasma.

Sodium chloride is also used in ophthalmology – when applied topically it has an anti-edema effect.

Indications

Isotonic solution: dehydration of various genesis. To maintain blood plasma volume during and after operations. As a solvent for various drugs.

Hypertensive solution: disorders of water-electrolyte exchange: sodium and chlorine ion deficiency; hypoosmolar dehydration of various genesis (due to prolonged vomiting, diarrhea, burns; during gastric fistula, pulmonary bleeding, intestinal bleeding).

Eye drops and ointment: corneal irritation in inflammatory and allergic diseases (in combination therapy).

Active ingredient

Composition

Active ingredient:

Sodium chloride 900 mg

How to take, the dosage

Isotonic sodium chloride solution is administered in/in, n/a and in enemas, and also used for washing wounds, eyes, nasal mucosa. Most often administered by IV, depending on the clinical situation – up to 3 liters per day.

Hypertensive sodium chloride solution is administered by IV. A single dose for intravenous jet injection may be 10-30 ml. In conditions requiring immediate replenishment of sodium and chloride ions, the drug is administered by IV drops in a dose of 100 ml.

Topically and externally, depending on the dosage form used and the treatment regimen.

Interaction

Compatible with colloidal hemodynamic blood substitutes (mutual enhancement of effect).

When mixing with other medications, visual compatibility must be monitored (however, invisible and therapeutic incompatibilities are possible).

Special Instructions

With caution use large amounts of sodium chloride in patients with impaired renal excretory function, with hypokalemia. Administration of large amounts of the solution may lead to acidosis, hyperhydration, increased excretion of potassium from the body.

Hypertensive solution is not administered p/u and i/m.

On long-term use it is necessary to monitor the concentration of electrolytes in the plasma and daily diuresis.

The temperature of the infusion solution should be 38°C.

Contraindications

With caution:

Aldosteronism and other conditions associated with sodium retention in the body .

Use in renal dysfunction

Cautious use of large amounts of sodium chloride in patients with impaired renal excretory function.

Side effects

Possible: nausea, vomiting, diarrhea, stomach cramps, thirst, lacrimation, sweating, fever, tachycardia, arterial hypertension, impaired renal function, edema, shortness of breath, headache, dizziness, restlessness, weakness, twitching and hypertonicity of muscles.

There have been no known adverse reactions when used topically or topically.

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