Sinestrol, 2% 1 ml 10 pcs

Synestrol has an estrogenic effect.

Estrogen, a derivative of stilbene, has estrogenic activity equivalent to estrone (a natural follicular hormone necessary for normal development of the female body). Together with the corpus luteum hormone, follicular hormone is involved in the regulation of the menstrual cycle.

Estrogens, by interacting with specific receptors, influence target organs. Under their influence in the fallopian tubes, cervix, vagina, external genitalia and mammary ducts the proliferation of epithelium occurs. Increases the sensitivity of uterine muscles and fallopian tubes to stimulating their motility.

It has a hypolipidemic effect, increases the blood content of alpha-lipoproteins and sensitivity to insulin, and improves glucose utilization. In high doses estrogens retain water and Na+ in the body, inhibit erythropoiesis. In high doses inhibit and in low doses activate FSH secretion.

The circulation of large amounts of estrogens in the blood for a short time promotes ovulatory type LH production. Hexestrol alleviates pathological menopause in women, prevents the development of postmenopausal osteoporosis, eliminates general disorders arising in women on the basis of ovarian hypofunction after gynecological operations.

Indications

ovarian hypofunction,
amenorrhea,
infertility,
climacteric disorders in women,
prostate adenoma,
prostate and breast cancer.

Pharmacological effect

Sinestrol has an estrogenic effect.

Estrogen is a derivative of stilbene; its estrogenic activity is equivalent to estrone (a natural follicular hormone necessary for the normal development of the female body). Together with the corpus luteum hormone, follicular hormone is involved in the regulation of the menstrual cycle.

Estrogens, interacting with specific receptors, affect target organs. Under their influence, epithelial proliferation occurs in the fallopian tubes, cervix, vagina, external genitalia, and excretory ducts of the mammary glands. Increases the sensitivity of the muscles of the uterus and fallopian tubes to drugs that stimulate their motor skills.

It has a hypolipidemic effect, increases the level of alpha-lipoproteins in the blood and sensitivity to the action of insulin, improves glucose utilization. In large doses, estrogens retain water and Na+ in the body and inhibit erythropoiesis. In large doses it inhibits, and in small doses it activates the secretion of FSH.

Circulation in the blood of large quantities of estrogens for a short time promotes the ovulatory type of LH production. Hexestrol facilitates the course of pathological menopause in women, prevents the development of postmenopausal osteoporosis, and eliminates common disorders that arise in the body of women due to ovarian hypofunction after gynecological operations.

Active ingredient

Hexestrol

Composition

1 ampoule with 1 ml of injection solution in peach oil contains:

Active substance:

hexestrol 20 mg.

Contraindications

liver diseases,
kidney diseases.

Side Effects

dizziness,
nausea,
vomit,
liver dysfunction,
endometrial hyperproliferation,
metrorrhagia,
feminization.

Interaction

Antiestrogenic drugs (clomiphene, etc.), used to treat infertility, can block estrogen receptors and weaken the effect of estrogens.

Folic acid and thyroid medications enhance the effect of hexestrol.

Hexestrol increases the effectiveness of lipid-lowering and antiarrhythmic drugs; weakens the effects of male sex hormones, diuretics and anticoagulants.

Manufacturer

Dalkhimfarm, Russia