Rosex, cream 0,75% 30 g

The active ingredient of the cream is metronidazole, which has antiparasitic and antimicrobial properties and is active against many pathogenic microorganisms.

Metronidazole is particularly effective against papulopustular inflammatory elements of rosacea.

The mechanism of action also appears to include an anti-inflammatory effect.

The drug is active against Gram-negative aerobic microorganisms: Helicobacter pylori; anaerobic microorganisms: Bacteroides fragilis, Bifidobacterium, Bilophila, Clostridium, Clostridium difficile, Clostridium perfringens, Eubacterium, Fusobacterium, Peptostreptococus, Prevotella, Prophyromonas, Veillonella; protozoa: Entamoeba histolytica, Glardia intestinalis, Tichomonas vaginalis.

The drug is resistant to: Gram-positive aerobic microorganisms – Actinomyces; anaerobic – Mobiluncus, Propionibacterium acnes.

Indications

Treatment of rosacea.

Pharmacological effect

The active component of the cream is metronidazole, which has antiparasitic and antimicrobial properties and is active against many pathogenic microorganisms.

Metronidazole is especially effective against papulopustular inflammatory elements of rosacea.

The mechanism of action appears to also include an anti-inflammatory effect.

The drug is active against gram-negative aerobic microorganisms: Helicobacter pylori; anaerobic microorganisms: Bacteroides fragilis, Bifidobacterium, Bilophila, Clostridium, Clostridium difficile, Clostridium perfringens, Eubacterium, Fusobacterium, Peptostreptococus, Prevotella, Prophyromonas, Veillonella; protozoa: Entamoeba histolytica, Glardia intestinalis, Tichomonas vaginalis.

The following are resistant to the drug: gram-positive aerobic microorganisms – Actinomyces; anaerobic – Mobiluncus, Propionibacterium acnes.

Special instructions

The use of Rosex cream should be temporarily suspended or permanently discontinued if adverse events develop.

Avoid contact of the cream with mucous membranes. In case of accidental contact, rinse thoroughly with warm water.

During treatment, solar or artificial ultraviolet irradiation should be avoided.

Active ingredient

Metronidazole

Composition

100 g of cream contains:

Metronidazole 0.75 g

Excipients:

benzyl alcohol,

isopropyl palmitate,

glycerol,

sorbitol 70% non-crystalline,

emulsion wax,

lactic acid or sodium hydroxide,

purified water

Pregnancy

There have been no controlled clinical trials of the drug during pregnancy and lactation.

Animal studies have shown that the drug does not have a toxic effect on the fetus and does not cause developmental defects.

Rosex cream does not pass into breast milk.

The use of Rosex cream during pregnancy and breastfeeding is possible in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

Contraindications

– Hypersensitivity.
– Pregnancy.
– Lactation period.

Overdose

Cases of overdose have not been described.

Storage conditions

At a temperature not exceeding 25 °C (do not freeze)

Shelf life

3 years

Manufacturer

Galderma Laboratories, France