Ringer’s solution, 500 ml

Compensates for energy substrate deficiencies, compensates for electrolyte and extracellular fluid deficiencies.

Indications

– As a plasma substitute when there is no need for red blood cell replacement, including. In shock, collapse, burns, frostbite, prolonged vomiting, diarrhea;

– for correction of water-electrolyte balance in acute spilt peritonitis and intestinal obstruction, intestinal fistula;

– dehydration of various etiologies;

– metabolic alkalosis accompanied by fluid loss.

Composition

How to take, the dosage

Intravenously by drip at a rate of 60-80 drops/min or by jetting.

The daily dose for adults is 5-20 ml/kg; if necessary, it can be increased to 30-50 ml/kg.

The daily dose for children is 5-10 ml/kg, the rate of administration is 30-60 drops/min, in shock dehydration initially administered 20-30 ml/kg.

The course of treatment is 3-5 days.

Interaction

Increased sodium retention in the body is possible with the simultaneous use of the following drugs: NSAIDs,
androgens, anabolic hormones, estrogens, corticotropin, mineralocorticoids, vasodilators or ganglioblocators.

The risk of hyperkalemia is increased when taken with potassium-saving diuretics, ACE inhibitors and potassium preparations.

In combination with cardiac glycosides, the likelihood of their toxic effects increases.

Special Instructions

Long-term use requires monitoring of plasma electrolyte concentrations and daily diuresis.

Because of the high level of chloride ions, long-term use of the drug is not recommended.

If a large volume is administered rapidly, the acid-base state and electrolyte levels should be monitored. Changes in blood pH (acidification) lead to redistribution of potassium ions (decrease of pH leads to increase of potassium ions in blood serum).

Only intact vials, with a clear solution, may be used!

Contraindications

– hypernatremia;

– hyperchloremia;

– acidosis;

– chronic heart failure;

– pulmonary edema;

– brain edema;

– chronic renal failure;

– hypervolemia;

– concomitant therapy with glucocorticosteroids;

– hypersensitivity to components of the drug.

Side effects

Hyperhydration, hypokalemia, allergic reactions.

Overdose

An overdose of the drug is extremely rare. As a rule, it leads to an increase in the frequency and severity of adverse reactions.

In this case it is recommended that the solution be discontinued and the dosage adjusted.