Primafungin, vaginal suppositories 100 mg 3 pcs

Primafungin is an antifungal polyene antibiotic of the macrolide group with a broad spectrum of action. It has a fungicidal effect. Natamycin binds sterols of cell membranes, disrupting their integrity and function, which leads to the death of microorganisms.

It is active against most pathogenic yeast-like fungi (especially Candida albicans), dermatophytes (Trichophyton, Microsporum, Epidermophyton), yeasts (Torulopsis, Rhodotorula), other pathogenic fungi (Aspergillus, Penicillium, Fusarium, Cephalosporium) and against some protozoa (trichomonads). It has no effect on Gram-positive and Gram-negative bacteria.

Resistance to natamycin in clinical practice does not occur.

Pharmacokinetics

It has no systemic action as it is practically not absorbed from the surface of mucous membranes. Vaginal suppositories under the influence of body temperature melt, forming a volumetrically spreading frothy mass, which contributes to the uniform distribution of the active substance in the mucous membrane.

Indications

Fungus, Molontic (candidiasis), Inflammation of the female genitalia, Candidiasis prevention, Itching and dryness in the genital area, Prevention of fungal diseases

Fungal lesions of the vulva and vagina; for preventive purposes when treated with cytostatics, glucocorticoids or broad spectrum antibiotics.

Active ingredient

Natamycin

Composition

Active ingredient:

Natamycin 100 mg.

Associates:

Cetyl alcohol 390 mg,

sorbitan trioleate 460 mg, <

Polysorbate 80 460 mg,

sodium bicarbonate 69 mg,

adipic acid 64 mg,

Supocir AM (semi-synthetic glycerides) – enough to produce a suppository mass of 2.5 г.

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