Potassium orotate, tablets 500 mg 10 pcs

Orotic acid is one of the precursors of pyrimidine nucleotides that are part of nucleic acids, which are involved in the synthesis of protein molecules, so orotic acid salts are considered as substances of anabolic action and are used in disorders of protein metabolism, for their stimulation.

Potassium salt of orotic acid (potassium orotate) is usually used.

Potassium orotate stimulates the synthesis of nucleic acids, albumin production in the liver (especially in conditions of prolonged hypoxia), increases appetite and has diuretic and regenerating properties.

Indications

Active ingredient

Composition

1 tablet contains:

active ingredient -potassium orotate 500 mg;

excipients:

Lactose monohydrate 66.0 mg,

Medical gelatin 3.0 mg,

stearic acid 7.4 mg,

potato starch to give a tablet weight of 750.0 mg.

How to take, the dosage

It should be taken orally 1 hour before a meal or 4 hours after a meal.

Adults take 250-500 mg 2-3 times a day. The course of treatment lasts on average 20-30 days.

If necessary the treatment can be repeated in 1 month. In exceptional cases it is possible to increase the dose of adults up to 3 g per day.

In children – 10-20 mg/kg of body weight per day divided into 3-4 doses (for example, if the body weight of the child is 25 kg the allowed dose is from 25 x 10 = 250 mg (1/2 tablet) to 25 x 20 = 500 mg (1 tablet/day divided into 3-4 doses).

The course of treatment is 3-5 weeks.

Interaction

Potassium orotate slightly reduces the toxicity of cardiac glycosides; the effect is increased when it is combined with magnesium preparations. Astringents and coagulants may slightly reduce absorption of potassium orotate in the gastrointestinal tract.

Potassium orotate hinders absorption of iron, tetracycline, sodium fluoride (interval between doses of the drug – at least 2-3 hours).

The oral contraceptives, myorelaxant diuretics, glucocorticosteroids, insulin reduce the effect of the drug.

Special Instructions

During treatment it is desirable to follow a diet.

Impact on the ability to drive vehicles and mechanisms.

It does not cause drowsiness and decrease the speed of psychomotor reactions.

Contraindications

Side effects

Usually Potassium orotate is well tolerated.

In isolated cases, allergic skin reactions may occur, which disappear after interruption of treatment.

Potassium orotate may also cause mild digestive disorders (nausea, vomiting).

When used in high doses against a low-protein diet, liver dystrophy may develop.

Overdose

There are no data on overdose.