Potassium orotate, tablets 500 mg 10 pcs

Orotic acid is one of the precursors of pyrimidine nucleotides that are part of nucleic acids, which are involved in the synthesis of protein molecules, so orotic acid salts are considered as substances of anabolic action and are used in disorders of protein metabolism, for their stimulation.

Potassium salt of orotic acid (potassium orotate) is usually used.

Potassium orotate stimulates the synthesis of nucleic acids, albumin production in the liver (especially in conditions of prolonged hypoxia), increases appetite and has diuretic and regenerating properties.

Indications

As an adjuvant for diseases of the liver and biliary tract (caused by acute and chronic intoxication, with the exception of organic lesions of the liver and biliary tract);
as part of combination therapy for chronic heart failure and cardiac arrhythmias;
nutritional and nutritional-infectious malnutrition in children;
chronic physical overstrain.

Pharmacological effect

Orotic acid is one of the precursors of pyrimidine nucleotides that are part of nucleic acids that are involved in the synthesis of protein molecules, and therefore, orotic acid salts are considered as anabolic substances and are used for protein metabolism disorders, to stimulate them.

The potassium salt of orotic acid (potassium orotate) is usually used.

Potassium orotate stimulates the synthesis of nucleic acids, albumin production in the liver (especially under conditions of prolonged hypoxia), increases appetite, and has diuretic and regenerative properties.

Special instructions

During the treatment period, it is advisable to follow a diet.

Impact on the ability to drive vehicles and machinery.

Does not cause drowsiness or decrease the speed of psychomotor reactions.

Active ingredient

Orotic acid

Composition

1 tablet contains:

active substance – potassium orotate 500 mg;

excipients:

lactose monohydrate 66.0 mg,

medical gelatin 3.0 mg,

stearic acid 7.4 mg,

potato starch to obtain a tablet weighing 750.0 mg.

Contraindications

Hypersensitivity to any of the components of the drug;
acute and chronic organic liver damage;
ascites;
nephrourolithiasis;
renal failure;
lactose intolerance;
lactase deficiency;
glucose-galactose malabsorption;
age up to 3 years.

With caution: during pregnancy and breastfeeding.

Side Effects

Potassium orotate is usually well tolerated.

In some cases, allergic skin reactions may occur, which disappear after interruption of treatment.

Potassium orotate may also cause mild digestive upset (nausea, vomiting).

When used in high doses on the background of a low-protein diet, liver dystrophy may develop.

Interaction

Potassium orotate slightly reduces the toxicity of cardiac glycosides; the effect increases when combined with magnesium preparations. Astringents and coating agents may slightly reduce the absorption of potassium orotate in the gastrointestinal tract.

Potassium orotate complicates the absorption of iron, tetracycline, sodium fluoride (the interval between taking the drug is at least 2-3 hours).

Oral contraceptives, diuretics, muscle relaxants, glucocorticosteroids, insulin reduce the effect of the drug.

Overdose

There are no data on overdose.

Storage conditions

In a dry place, out of reach of children, at a temperature not exceeding 25°C.

Shelf life

4 years.

Manufacturer

ABVA RUS, Russia