Poliginax, vaginal capsules 12 pcs

Polyjinax is an antifungal topical, antibacterial.

Pharmacodynamics

A combined drug, the action of which is caused by its constituent components. It has antibacterial, bactericidal and antifungal action.

Neomycin and polymyxin B are active against many Gram-negative and Gram-positive microorganisms. Streptococcus spp. and anaerobic bacteria are insensitive to these antibiotics.

Nistatin has a fungicidal effect against fungi of the genus Candida.

It improves trophic processes in the vaginal mucosa.

Pharmacokinetics

Distributes evenly throughout the vaginal mucosa with a local bactericidal and fungicidal effect. It is practically not absorbed from the surface of the vaginal mucosa.

Indications

Treatment of non-specific, fungal, mixed vaginitis, vulvovaginitis and cervicovaginitis; prevention of infection before genital surgery, intrauterine diagnostic procedures, childbirth, before and after cervical diathermic coagulation.

Active ingredient

Composition

Active ingredients:

Neomycin sulfate 35000 IU;

Polymyxin B sulfate 35000 IU;

Nistatin 100000 IU;

Associated substances:

Tefoz 63® – 125 mg;

Hydrogenated soybean oil – 30 mg;

dimethicone 1000 – up to 2500 mg;

Capsule shell:

gelatin, 381.2 mg; glycerol, 191.5 mg; dimethicone 1000, 86.9 mg

How to take, the dosage

Intravaginally. Lying on your back, 1 capsule is inserted deep into the vagina in the evening before going to bed. The course of treatment is 12 days. The prophylactic course is 6 days.

If 1 or more doses are missed, the drug should be restarted in the usual dose.

Interaction

It is not recommended to use in combination with spermicides, because the activity of the drug may decrease.

Special Instructions

Pre-application of the drug requires prior swabbing and bacteriological analysis.

The period of use of the drug should be limited in order to prevent the development of resistance to it by individual pathogens and the risk of reinfection.

Latex caps and condoms are not recommended during treatment.

The treatment should not be interrupted during menstruation.

Impact on the ability to drive vehicles and other mechanisms. There are no data on the negative effect of the drug on the ability to drive vehicles and other mechanisms.

Contraindications

Hypersensitivity to any component of the drug; I trimester of pregnancy.

Side effects

Allergic reactions, burning, itching, irritation in the vagina. Allergic contact eczema. With long-term use, systemic side effects of aminoglycosides are possible.

If any of the side effects listed in the description worsen, or if the patient notices any other side effects not listed in the description, the physician should be informed.

Pregnancy use

The use during pregnancy (in the second and third trimesters) is possible only by prescription when the expected benefits to the mother exceed the potential risk to the fetus;

Lactation period is contraindicated; if it is necessary to use the drug during this period, breastfeeding should be stopped.

Similarities