Pimafucin, vaginal suppositories 100 mg 6 pcs
€13.70 €11.42
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Pharmacological group
The drug with antifungal action for local use in gynecology.
Pharmacological action
Antifungal polyenic antibiotic of the macrolide group with a broad spectrum of action. It has a fungicidal effect. Natamycin binds sterols of the cell membrane of the fungus, disrupting its integrity and function, which leads to cell death.
Pharmacodynamics
Natamycin is sensitive to most pathogenic yeast fungi, especially Candida albicans. Dermatophytes are less sensitive to natamycin. Resistance to natamycin has not been noted in clinical practice.
Pharmacokinetics
When applied to the skin and mucous membranes, it is practically not subject to systemic absorption, so it has no systemic action.
Indications
Active ingredient
Composition
Vaginal suppositories are torpedo-shaped, white with a yellowish tinge to light yellow with a brownish tinge.
1 suppository contains:
Active substances:
natamycin 100 mg.
Associates:
Cetyl alcohol – 690 mg,
solid fat – 700 mg,
sorbitan trioleate – 460 mg,
polysorbate 80 – 460 mg,
sodium bicarbonate – 69 mg,
adipic acid – 64 mg.
There are 3 suppositories in the aluminum foil tube.
There are 2 aluminum foil suppositories in the package.
How to take, the dosage
Method of administration and dosing regimen depending on the disease
Prescribe 1 vaginal suppository for 3-6 days. The suppository is inserted into the vagina in the supine position, as deeply as possible, once a day at night.
In case of persistent vaginitis caused by Candida albicans Pimafucin® is additionally prescribed in the form of oral tablets (1 tablet 4 times daily for 10-20 days) to sanitize the focus of Candida infection in the gut.
Pimafucin® in a cream form is used for the treatment of candidal genital infection of the partner.
The duration of treatment is determined individually.
After symptoms of the disease have disappeared, it is recommended to continue treatment for a few more days.
Interaction
Drug interactions of the drug Pimafucin® with other medicinal products have not been found.
Special Instructions
Precautionary measures when taking the drug
Vaginal suppositories dissolve rapidly under the influence of body temperature, forming a frothy mass, which contributes to an even distribution of the active substance.
In cases of chronic or recurrent infection, local treatment may be supplemented by prescription of Pimafucin in the form of tablets and cream for external use.
Cetyl alcohol, which is included in the vaginal suppositories, may cause a mild burning sensation if there is hypersensitivity to this component.
The therapy with suppositories is interrupted during menstruation.
When using the suppositories it is not necessary to exclude sexual intercourse. However, it is recommended to conduct an examination of sexual partners and, if candidiasis is detected, to carry out a course of treatment with Pimafucin. Also, barrier contraception should be used during treatment.
Impact on the ability to drive vehicles and other mechanisms requiring high concentration
Pimafucin® does not affect the ability to drive vehicles and operate machinery.
Interaction with alcohol
There are no data on interaction with alcohol.
Prescription conditions of pharmacies
The drug is approved for over-the-counter use.
Contraindications
The contraindication to the use of Pimafucin is:
Side effects
When using Pimafucin:
Local reactions: mild irritation, burning sensation.
Overdose
At present, no cases of Pimafucin® overdose have been reported.
Pregnancy use
Pimafucin can be used during pregnancy and lactation.
There are no data on adverse effects on the fetus.
Similarities
Weight | 0.026 kg |
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Shelf life | 2 years |
Conditions of storage | At a temperature not exceeding 25 °C |
Manufacturer | Temmler Italia S.r.l., Italy |
Medication form | vaginal suppositories |
Brand | Temmler Italia S.r.l. |
Other forms…
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