Pimafucin, 100 mg 20 pcs

Name: Pimafucin, 100 mg 20 pcs
SKU: 34210
Availability: OutOfStock

€16.10

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EAN: 5702191012729 SKU: 34210 Categories: Antifungal, Medicine

Description

Antifungal polyene (tetraene) antibiotic from the macrolide group. It has a predominantly fungicidal effect. Natamycin irreversibly binds to the ergosterol of the cell membrane of the fungus, which leads to violation of its integrity, loss of cytoplasmic content and cell death.

Pharmacodynamics

The majority of pathogenic yeasts and molds including genera Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium are sensitive to natamycin. Dermatophytes and Pseudoallescheria boydii are less sensitive to natamycin. Cases of resistance to natamycin in clinical practice have not been noted. Natamycin in the dosage form of enteric coated tablets acts only in the intestinal lumen.

Pharmacokinetics

In oral administration natamycin is practically not absorbed from the gastrointestinal tract and has no systemic action.

Indications

Candida prophylaxis, Intestinal Candida, Lactus (candidiasis)

Candida intestinalis;
.Acute pseudomembranous and acute atrophic candidiasis in patients with cachexia, immunodeficiency, and after therapy with antibiotics, corticosteroids, cytostatics;
Sanation of intestinal reservoir of Candida fungi in skin and mucosal candidiasis, including.Candida vaginitis, vulvovaginitis and vulvovaginitis.

Active ingredient

Natamycin

Composition

Active substances:

Natamycin 100 mg.

Auxiliary substances:

Potato starch – 79.2 mg,

povidone K30 – 5 mg,

magnesium stearate – 2.5 mg,

lactose monohydrate – 66 mg.

Composition of the shell:

cellacephate – 18 mg,

triacetin – 2.7 mg,

p> sucrose – 122 mg,

methylparahydroxybenzoate – 0.07 mg,

calcium carbonate – 30 mg,

kaolin – 14.2 mg,

talc – 21.7 mg,

titanium dioxide – 3 mg,

acacia gum – 7.3 mg,

gelatin – 3.3 mg,

beeswax white – 0.13 mg.

How to take, the dosage
How to take, the dosage
The drug is taken orally. Food intake has no effect on the effectiveness of the drug.
The dosage regimen for different age groups and depending on the disease
In intestinal candidiasis:
Dosage for adults – 100 mg (1 tablet) recommended.) 4 times a day;
Dosage for children – 100 mg (1 tablet) 2 times a day.
Pimafucin® tablets (orally 100 mg (1 tablet) 4 times a day for 10 – 20 days) may be used together with antifungal drugs (for example, Pimafucin® suppositories) for sanation of the focus of candida infection in the intestine.
The duration of treatment is determined individually. After disappearance of symptoms it is recommended to continue treatment for a few more days.

Interaction
Interaction
Drug interactions of Pimafucin® with other medicinal products were not detected.

Special Instructions
Special Instructions
Patients with rare congenital galactose intolerance, fructose intolerance, lactase lapp deficiency, glucose-galactose malabsorption or sucrose-isomaltase deficiency should take into account that the drug contains lactose monohydrate (66 mg) and sucrose (122 mg). If the patient suffers from one of the above mentioned diseases, before taking Pimafucin® tablets, it is necessary to consult a doctor.
Pimafucin® in this dosage form is not recommended for use in infants because of possible difficulty in swallowing the pills.
Impact on ability to drive vehicles and other mechanisms requiring increased concentration
Pimafucin® does not affect the ability to drive vehicles and mechanisms.
Interaction with alcohol
There are no data on interaction with alcohol.
Prescription conditions from pharmacies
The drug is approved for over-the-counter use.
.

Contraindications
Contraindications
High sensitivity to the drug’s components
.

Side effects
Side effects
When using Pimafucin:
In the digestive system: nausea, diarrhea may occur (occurring in the first days of taking the drug and passing on its own during treatment).
The patient should be warned that if any of the side effects mentioned in the instructions worsen, or if he notices any other side effects not mentioned in the instructions, he should tell his doctor.

Overdose
Overdose
At present, no cases of overdose of Pimafucin® have been reported.

Similarities
Similarities
Pimafucin, Primafungin, Ecofucin, Natamycin

Additional information
Weight 0.066 kg
Shelf life
4 years
Conditions of storage
At a temperature not exceeding 25 °C
Manufacturer
Haupt Pharma Wulfing GmbH, Germany
Medication form
enteric soluble tablets
Brand
Haupt Pharma Wulfing GmbH