Piaskledin 300, capsules 30 pcs

Pharmaceutical group:

Pharmaceutical regulating metabolism in cartilage.

Pharmaceutical action:

Piascledine 300 regulates the metabolic processes in the cartilage. It has anti-inflammatory and analgesic effect on the joints. Helps to slow down the degenerative process in the cartilage of the joints, reduces pain associated with this process, restores motor function. Experimental studies have shown that the product has a regenerating effect on cartilage by stimulating the synthesis of collagen in joint chondrocytes.

The unsaponifiable compounds of soybean oil and avocado oil:

• increase collagen production and inhibit the stimulatory effect of IL-1 on collagenase synthesis;
• increase the production of plasminogenesis activator inhibitor, thus reducing cartilage damage both indirectly by stimulating metalloproteinases and through direct action on cartilage by activating proteoglycan degradation, which prevents cartilage destruction;
• increase the action of transforming growth factor β1 (TGF) in chondrocytes, which has an anabolic effect;
• regulate the synthesis of macromolecules of intercellular substance of articular cartilage, are a stimulator of synthesis of macromolecules of hyaline cartilage as well as periodontal tissue, preventing tooth loss.

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Indications

Comprehensive therapy of osteoarthritis of knee and hip joints of stage I-III; adjuvant therapy of periodontitis.

Active ingredient

Composition

Active substances:

avocado oil unsaponifiable compounds 100 mg;

soybean oil unsaponifiable compounds 200 mg;

Capsule composition:

titanium dioxide (E171);

gelatin;

Associates:

Butylhydroxytoluene;

Silicon dioxide colloidal.

How to take, the dosage

In the morning, orally, with meals.

1 capsule of the drug Pisquedin 300 a day with 250 ml of water.

The course of treatment is 6 months.

Special Instructions

In the initial phase of treatment, the administration of Piascledine 300 may be combined with the administration of NSAIDs and/or analgesics. As the effect of PisCledine 300 increases, the dose of NSAIDs may be reduced.

Piascedine 300 can be used by drivers of vehicles, athletes, as it does not affect the patient’s ability to drive a car or engage in dangerous activities requiring increased concentration.

Contraindications

Side effects

Allergic reactions are possible.

Pregnancy use

It is contraindicated in pregnancy.

Breastfeeding should be stopped during treatment.