Pharmatex, vaginal tablets 20 mg 12 pcs

Indications

Local contraception for women of reproductive age, and especially:
– if there are contraindications to the use of hormonal contraceptives or intrauterine contraception;
– in the postpartum period, during breastfeeding, in premenopause;
– when occasional contraception is required;
– as an additional method of contraception when using a vaginal diaphragm, cervical cap, condom or intrauterine device (especially with long-term use of certain medications, such as non-steroidal anti-inflammatory drugs);
– as an additional method of contraception if you miss or are late in taking oral hormonal contraceptives. In this case, it is recommended to combine both methods of contraception during the remaining days of the menstrual cycle.
The use of the drug Farmatex significantly reduces the risk of pregnancy, but does not eliminate it completely.
The effectiveness of the drug depends on compliance with the recommendations for use.

Pharmacological effect

Pharmacotherapeutic group:

Contraceptive for topical use.

ATX code: G02BB

Pharmacological properties:

Pharmacodynamics

Myristalkonium chloride is both a spermicide and an antiseptic. The spermicidal effect is due to the ability of the active substance to destroy the membranes of sperm (first flagella, then heads), which leads to the impossibility of fertilization of the egg by damaged sperm.

The drug does not affect the normal microflora of the vagina (including lactobacilli).

Pharmatex is not a hormonal drug and does not affect the menstrual cycle, libido or fertility.

Myristalkonium chloride has antiseptic activity. In vitro, the drug is active against Neisseria gonorrhoeae, Chlamydia spp., Herpes simplex type 2, HIV, Trichomonas vaginalis, Staphylococcus aureus.

Has no effect on Mycoplasma spp. and shows low activity against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.

Pharmacokinetics

The absorption of myristalkonium chloride by the vaginal mucosa is very low.

Conducted preclinical studies of pharmacological safety, toxicity after repeated administration, genotoxicity, carcinogenic potential, reproductive toxicity did not reveal any danger to humans.

Special instructions

Pharmatex is an effective drug for preventing pregnancy, provided it is used correctly during each sexual intercourse. However, spermicides are always less effective compared to hormonal contraception, intrauterine devices, diaphragm, cervical cap or condom.
The effectiveness of contraception depends on compliance with the rules for using the drug.

The following conditions must be met:
– Use the drug before each sexual intercourse, regardless of the period of the menstrual cycle, placing the vaginal tablet deep into the vagina.
– Do not use soap for toileting the genitals for both partners 2 hours before sexual intercourse and for 2 hours after sexual intercourse, since soap, even in residual quantities, destroys the active substance of the drug Farmatex.
– Toilet of the external genitalia is only possible with plain water for both partners. Vaginal irrigation (douching) can be used no earlier than 2 hours after sexual intercourse.
– With the drug Pharmatex inserted into the vagina, you should not take baths or swim in the sea, pool or reservoirs in order to avoid reducing its contraceptive effect.
– In case of occurrence or progression of inflammatory diseases, ulceration and irritation of the mucous membrane of the vagina or cervix, it is necessary to stop using the drug Farmatex.
– If treatment with drugs for vaginal use is necessary, you should temporarily stop using the drug Farmatex until the end of the course of treatment.

This method of contraception does not protect against sexually transmitted infections or infections caused by the human immunodeficiency virus. The only method of contraception that protects against contracting these diseases during sexual intercourse is the male or female condom (if used correctly).

Impact on the ability to drive:
There is no data on the negative effect of the drug on the ability to drive vehicles and machines.

Active ingredient

Myristalkonium chloride

Composition

Active ingredient: Myristalkonium chloride 20.0 mg.

Excipients: sodium bicarbonate, anhydrous citric acid, hydrated colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate, lactose monohydrate, macrogol 6000.

Pregnancy

Pregnancy
The drug is a contraceptive and is not used during pregnancy. In clinical and epidemiological studies, the accidental use of this spermicide in early pregnancy did not reveal the occurrence of fetal malformations.

Breastfeeding
Excretion into human milk is possible in extremely small quantities without any known negative consequences. The drug can be used during breastfeeding.

Contraindications

Hypersensitivity to the active substance of the drug or to any of the excipients of the drug, vaginitis, ulceration and irritation of the mucous membrane of the vagina and cervix.

Side Effects

Adverse reactions are listed according to the name of the system-organ classes and frequency of occurrence: very often (≥1/10), often (≥1/100, but <1/10), infrequently (≥1/1000, but <1/100), rarely (≥1/10000, but <1/1000), very rarely (<1/10000), frequency unknown (cannot be estimated from available data).

Disorders of the genital organs and breast

Rarely: itching, burning sensation or local irritation in one or both partners.

Immune system disorders

Frequency unknown: allergic reactions.

If they occur, you must stop using the drug Farmatex.

If any of the side effects indicated in the instructions get worse or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

– Any agent used intravaginally may reduce the spermicidal effect of the drug.
– The active substance, myristalkonium chloride, is destroyed by soap, so the use of soap for toileting the genitals is prohibited, even in minimal quantities.

Overdose

No cases of overdose have been reported.

Storage conditions

Store at a temperature not exceeding 25 °C.
Keep out of the reach of children.

Shelf life

3 years. Do not use after expiration date.

Manufacturer

Innotera Chouzy, France