Pharmatex, vaginal suppositories 10 pcs

Contraceptive for topical use.

ATX code: G02BB

Pharmacological properties

Pharmacodynamics

Benzalkonium chloride is both a spermicid and an antiseptic. The spermicidal effect is due to the ability of the active substance to destroy the membranes of sperm cells (first flagella, then heads), which leads to the inability to fertilize the egg with damaged sperm.
The effect develops 5 minutes after the insertion of the suppository in the vagina.

The use of the drug Farmatex significantly reduces the risk of pregnancy, but does not eliminate it completely.

Pharmatex has no effect on normal vaginal microflora (including Döderlein bacillus).

Pharmatex has no effect on the menstrual cycle, libido or fertility.

In vitro benzalkonium chloride is active against Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Herpes simplex type 2, Staphylococcus aureus. It has no effect on Mycoplasma spp. and weak effect on Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.

Pharmacokinetics

The absorption of benzalkonium chloride by the vaginal mucosa is very low. The drug is removed from the mucosal surface by simple washing with water and normal physiological secretions.

Indications

Local contraception for women of reproductive age, and especially:

– if there are contraindications to the use of hormonal contraceptives or intrauterine contraception;

– In the postpartum period, while breastfeeding; after termination of pregnancy;

– In premenopause;

– In case of irregular sexual intercourse;

– As additional local contraception when using a vaginal diaphragm, cervical cap, or other intrauterine contraceptives, especially with long-term use of medications such as NSAIDs (non-steroidal anti-inflammatory drugs).

As an additional method of contraception if you miss or are late in taking oral hormonal contraceptives. In this case, it is recommended to combine both methods of contraception for the remaining days of the menstrual cycle.

Active ingredient

Composition

Composition per 1 suppository (1.6 g):

The active substance:

Benzalkonium chloride 50% aqueous solution -b37.8 mg,

which corresponds to benzalkonium chloride – 18.9 mg

Excipients:

Hyprolose – 9.1 mg

Witepsol S 51 solid fat – 1553.1 mg.

How to take, the dosage

For vaginal use.

Lying on its back, the suppository is inserted deep into the vagina 5 minutes before intercourse. The duration of action is 4 hours. It is obligatory to insert a new suppository before each repeated intercourse.

Interaction

Any product used intravaginally may decrease the spermicidal effect of the drug.

The active ingredient, benzalkonium chloride, is destroyed by soap, so the use of genital soap, even in minimal amounts, is prohibited.

Special Instructions

The use of soap to wash the genitals 2 hours before and 2 hours after sexual intercourse is prohibited because soap destroys the active ingredient of Farmatex.

Toilet the external genitalia is possible only with plain water for both partners. Vaginal irrigation (douches) can be used not earlier than 2 hours after sexual intercourse.

With Farmatex injected into the vagina, you should not take a bath or swim in the sea, pools or bodies of water to avoid reducing its contraceptive effect.

If treatment with vaginal products is necessary, Pharmatex should be temporarily discontinued until the end of treatment.

This method of contraception does not protect against sexually transmitted infections or those caused by the human immunodeficiency virus. There is only one method of barrier contraception against these diseases: the condom.

Synopsis

Contraindications

High sensitivity to the components of the drug, vaginitis, ulceration and irritation of the mucous membrane of the vagina and cervix.

Side effects

Allergic reactions, contact dermatitis, itching and burning in the vagina and/or the partner’s penis, painful urination.

If these occur, discontinue use of Farmatex.

If any of the side effects listed in the instructions worsen, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose

There have been no recorded cases of overdose.

Pregnancy use

Pregnancy

The drug is a contraceptive and is not used during pregnancy.

Inadvertent use of this spermicide in early pregnancy has not shown any adverse effects on the fetus.
Breastfeeding

Infusion into breast milk is possible in very small amounts without any known adverse effects. The drug can be used during breastfeeding.