Panangin Forte, 316 mg+280 mg 60 pcs

Pharmacotherapeutic group: potassium and magnesium drug.
ATH code: A12CX

Pharmacodynamics
Essential intracellular potassium (K+) and magnesium (Mg++) cations play key roles in the function of numerous enzymes, in the formation of bonds between macromolecules and intracellular structures and in the mechanism of muscle contractility. The intra- and extracellular ratios of potassium, calcium, sodium, and magnesium ions influence myocardial contractility. Endogenous asparaginate acts as a conductor of ions: it has a high affinity for cells, due to the insignificant dissociation of its salts, ions in the form of complex compounds penetrate the cell. Magnesium asparaginate and potassium asparaginate improve myocardial metabolism.
Magnesium / potassium deficiency predisposes to the development of arterial hypertension, coronary atherosclerosis, arrhythmias and metabolic changes in myocardium.
Each tablet of Panangin® Forte preparation contains 280 mg of magnesium aspartate and 316 mg of potassium aspartate that is twice more content of active substances in Panangin®, film-coated tablets. The daily dose of Panangin® Forte: 1 tablet 3 times a day corresponds to the daily dose of Panangin®: 2 tablets 3 times a day. Taking a single dose of Panangin® Forte as a single tablet makes the treatment more convenient for the patient.

Pharmacokinetics
Potassium and magnesium asparginates are intensively absorbed in intestine, mainly in small intestine. It is excreted by the kidneys.

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