Oflomelid, ointment 30 g

Oflomelide has antimicrobial, anti-inflammatory, local anesthetic, regenerating effect.

Ofloxacin is a broad-spectrum antimicrobial agent of the group of fluoroquinolones. It has a bactericidal effect due to blockade of DNA-gyrase in bacterial cells. Highly active against Gram-positive microorganisms: Staphylococcus spp. (including Staphylococcus aureus, Staphylococcus epidermidis), Streptococcus spp.; Gram-negative microorganisms: Pseudomonas aeruginosa, Acinetobacter spp, Escherichia coli, Klebsiella spp., Proteus spp., Enterobacter spp., Citrobacter spp.; Anaerobes: Propionibacterium acnes;intracellular microorganisms: Chlamydia spp. (including Chlamydia trachomatis), Legionella spp., Mycoplasma spp.

Methyluracil is a tissue repair stimulator. It has anabolic activity. It accelerates the processes of cellular regeneration in wounds, accelerating growth and granulation maturation of tissue and epithelialization.

Lidocaine has a local anesthetic effect due to blockade of sodium channels which prevents generation of impulses in the endings of sensitive neurons and conducting impulses along the nerve fibers. When used externally it dilates blood vessels and has no local irritating effect.

The water-soluble hydrophilic (hyperosmolar) base of the ointment is the mixture of polyethylene oxides (polyethylene glycols) with molecular weight 400 and 1500 which provide the dehydrating (moisture-absorbing) effect on the tissue 20 times higher in strength than the 10% sodium chloride solution.

Indications

Infected septic wounds of different localization and etiology in the first (purulent-necrotic) phase of the wound process, including those accompanied by a pronounced pain syndrome:

Active ingredient

Composition

Active ingredients:

ofloxacin 10 mg;

dioxomethyltetrahydropyrimidine (methyluracil) 40 mg;

Lidocaine hydrochloride (in monohydrate form) 30 mg;

Associates:

Macrogol 1500 (polyethylene oxide 1500, low molecular weight polyethylene glycol 1500),

Macrogol 400 (polyethylene oxide 400, low molecular weight polyethylene glycol 400),

propylene glycol,

methyl parahydroxybenzoate (nipagin or methylparaben),

propylparahydroxybenzoate (nipazole or propylparaben)

How to take, the dosage

Oflomelide is used externally, once a day for 1-2 weeks. Maximum daily dose should not exceed 100 g of ointment. Duration of treatment depends on the dynamics of wound clearing of purulent exudate and the time of cessation of the inflammatory process.

After standard treatment of wounds and burns the ointment is applied directly to the wound surface with a thin layer (then a sterile gauze bandage is applied) or on a gauze bandage with subsequent application to the lesion area.

Tampons soaked in ointment loosely fill cavities of purulent wounds after their surgical treatment, and gauze turundas with ointment are inserted into fistulous passages.

In the treatment of infected burns the drug is used daily or 2-3 times a week depending on the amount of purulent discharge.

Interaction

There have been no drug-drug interactions that have resulted in decreased efficacy and safety of the drugs used.

Special Instructions

Consult a specialist before use.

Contraindications

Side effects

Possible: allergic reactions.

Pregnancy use

Oflomelide is contraindicated in children under 18 years of age, pregnant women and during lactation.