Mexiprim, 125 mg 30 pcs.

Mexiprim belongs to the heteroaromatic antioxidants.

It has a wide range of pharmacological activity: increases the body’s resistance to stress, exhibits anxiolytic effect, not accompanied by myorelaxant effect; has nootropic properties, prevents and reduces learning and memory disorders that occur with aging and exposure to various pathogenic factors; has anticonvulsant effect; exhibits antioxidant and antihypoxic properties; increases attention concentration and performance; weakens the toxic effects of alcohol.

The drug improves brain tissue metabolism and blood supply, improves microcirculation and blood rheology, reduces platelet aggregation.

Stabilizes membrane structures of blood cells (erythrocytes and platelets). It has hypolipidemic effect, decreases the total cholesterol and low-density lipoproteins.

The mechanism of action of Mexiprim is due to its antioxidant and membrane-protective effect.

It inhibits lipid peroxidation, increases superoxidase activity, increases lipid-protein ratio, decreases membrane viscosity and increases its fluidity.

Modulates the activity of membrane-bound enzymes (calcium-independent phosphodiesterase, adenylate cyclase, acetylcholinesterase), receptor complexes (benzodiazepine, GABA, acetylcholine) that increases their ability to bind to ligands, maintains structural and functional organization of biomembranes, neurotransport and improves synaptic transmission.

Mexiprim increases dopamine content in the brain.

Causes compensatory activation of aerobic glycolysis and a decrease in the degree of inhibition of oxidative processes in the Krebs cycle in hypoxia with an increase in ATP and creatine phosphate, activation of energy-synthesizing functions of mitochondria, stabilization of cell membranes.

Indications

Active ingredient

Composition

How to take, the dosage

Mexicaprim is administered orally.

Therapeutic doses used and duration of treatment are determined by the sensitivity of patients to the drug.

The treatment starts with a dose of 0.25-0.5 g; the average daily dose is 0.25-0.5 g, the maximum daily dose is 0.8 g. The daily dose of the drug is divided into 2-3 doses during the day.

To treat patients with anxiety disorders, autonomic-vascular dysfunctions and cognitive disorders Mexiprim is used for 2-6 weeks.

In relieving alcohol withdrawal syndrome Mexiprim is used for 5-7 days.

Course therapy with Mexiprim is completed gradually, reducing the dose of the drug over 2-3 days.

Interaction

Compatible with psychotropic drugs.

It enhances the effect of benzodiazepine anxiolytics, anticonvulsants (carbamazepine), anti-Parkinsonian drugs (levodopa), reduces the toxic effects of ethyl alcohol.

Special Instructions

Synopsis

Contraindications

Side effects

Overdose

Symptoms: sleep disturbance (insomnia, in some cases drowsiness).

Treatment: as a rule, it is not required – symptoms disappear on their own within a day. In severe cases of insomnia, it is recommended to take nitrazepam 10 mg, oxazepam 10 mg or diazepam 5 mg.

Pregnancy use

The possibility and safety of using Mexiprim in pregnancy and lactation is currently insufficiently studied, so the use of the drug in this category of patients is contraindicated.

Similarities