Mexifin, 50 mg/ml 2 ml 10 pcs
€8.06 €7.71
Mexifin belongs to the group of compounds of 3-oxypyridine and succinic acid and has antioxidant, antihypoxic, membrane stabilizing, nootropic, stress-protective, anticonvulsant and anxiolytic effects.
. Mexifin acts as an inhibitor of free radicals, inhibits lipid peroxidation, increases the activity of antioxidant enzyme system, restores the structure and function of membranes disturbed in various pathologies, modulates the effect on membrane-bound enzymes (calcium-independent phosphodiesterase, adenylate cyclase, acetylcholindinesterase), ion channels, receptor complexes, including benzodiazepine, GABA, acetylcholine; improves transport of neurotransmitters, synaptic transmission and interconnection of brain structures.
Enhances content of dopamine in the brain. The mechanism of action of mexiphine is due to its ability to enhance compensatory activation of aerobic glycolysis. It decreases the degree of inhibition of oxidative processes in the Krebs cycle in hypoxia by increasing the content of ATP and creatine phosphate, helps to maintain the structural and functional organization of biomembranes.
Mexifin improves cerebral metabolism and blood supply of the brain, corrects disorders in the regulatory and microcirculatory systems by inhibiting constriction of arterioles and precapillaries; Improves blood rheology by reducing platelet aggregation, stabilizing membrane structures of blood cells (erythrocytes and platelets), prevents hemolysis; improves immune system activity.
Mexifin has anti-atherogenic effect, causing regression of atherosclerotic changes in the arteries, reducing levels of cholesterol and low-density lipoproteins and restoring lipid homeostasis.
Mexifin improves performance and resistance to various extreme damaging factors of oxygen-dependent pathological conditions (shock, stress, hypoxia and ischemia, cerebral blood flow disorders, physical and mental overload), intoxication with alcohol and antipsychotic drugs (neuroleptics).
Indications
Active ingredient
Composition
Active substance:
ethylmethylhydroxypyridine succinate – 50 mg;
Auxiliary substance – water for injection
How to take, the dosage
Mexifin is administered intramuscularly or intravenously (by trickle or drip). Doses are chosen individually. Duration of treatment and dosing regimen depends on the severity of the patient’s condition and effectiveness of treatment. Treatment starts with a dose of 50-100 mg 1-3 times a day, gradually increasing the dose to obtain therapeutic effect. The maximum daily dose should not exceed 800 mg.
In case of infusion method the drug should be diluted in physiological sodium chloride solution.
Mexifin is administered by jetting slowly over 5-7 minutes; by drip – at a rate of 60 drops per minute.
Acute cerebral circulation disorders: as part of combined therapy, 200-300 mg intravenously by drip for the first 2-4 days, then 100 mg intramuscularly 3 times a day. Course duration is 10-14 days.
Discirculatory encephalopathy (decompensation phase): intravenously by shot or dropwise by 100 mg 2-3 times per day for 14 days followed by intramuscular injection by 100 mg per day for further 14 days.
Prevention of discirculatory encephalopathy: intramuscularly 100 mg 2 times daily for 10-14 days.
Mild cognitive impairment in elderly patients and in patients with anxiety disorders: intramuscularly 100-300 mg daily for 14-30 days.
Alcohol withdrawal syndrome: 100-200 mg intramuscularly 2-3 times a day or intravenous drip 1-2 times a day for 5-7 days.
Acute intoxication with neuroleptics: intravenously 50-300 mg per day for 7-14 days depending on the severity of the condition.
In cases of neurotic disorders and vascular dystonia the drug is prescribed intramuscularly in a dose of 50-400 mg per day for 14 days.
Contraindications
Hypersensitivity to oxymethylpyridine succinate and/or pyridoxine, acute liver and kidney dysfunction, pregnancy, lactation.
Side effects
Nausea, dry mouth, allergic reactions.
Pregnancy use
Contraindicated
Similarities
Weight | 0.057 kg |
---|---|
Shelf life | 3 years |
Conditions of storage | In a dry, light-protected place at a temperature not exceeding 25 °C |
Manufacturer | FGUP Pharmzaschita NPC, Russia |
Medication form | solution |
Brand | FGUP Pharmzaschita NPC |
Related products
Buy Mexifin, 50 mg/ml 2 ml 10 pcs with delivery to USA, UK, Europe and over 120 other countries.