Megaflox, 400 mg 5 pcs

Lung inflammation (pneumonia), Infectious diseases, Bronchitis, Sinusitis, Respiratory tract infections, Urinary tract infections, Skin infections

Infections of the upper and lower airways: acute sinusitis, exacerbation of chronic bronchitis, outpatient pneumonia; skin and soft tissue infections.

Active ingredient

Composition

1 tablet contains moxifloxacin hydrochloride 436.8 mg, which corresponds to the content of moxifloxacin 400 mg

Excipients:

cellulose microcrystalline – 161.2 mg,

povidone (K-30) – 18 mg,

croscarmellose sodium – 70 mg,

colloidal silicon dioxide (aerosil) – 7 mg,

magnesium stearate – 7 mg.

Composition of the film coating:

Opadray II (series 85), incl.including polyvinyl alcohol – 8.4 mg,

macrogol – 4.242 mg,

talc – 3.108 mg,

titanium dioxide – 4.916 mg,

aluminum varnish based on azorubin dye – 0.094 mg,

aluminum varnish based on sunshine yellow dye – 0.118 mg.

How to take, the dosage

Internal, 400 mg once a day.

The course of treatment in exacerbation of chronic bronchitis – 5 days, outpatient pneumonia – 10 days, acute sinusitis, skin and soft tissue infections – 7 days.

Interaction

When used concomitantly antacids, minerals, multivitamins impair absorption (due to the formation of chelate complexes with polyvalent cations) and reduce the concentration of moxifloxacin in plasma (simultaneous use is possible with an interval of 4 hours before or 2 hours after taking moxifloxacin).

When receiving moxifloxacin against the background of other fluoroquinolones the development of phototoxic reactions is possible.
Ranitidine reduces absorption of moxifloxacin.

Special Instructions

With caution moxifloxacin is prescribed in epilepsy syndrome (including history), epilepsy, liver failure, QT interval prolongation syndrome.

In therapy with fluoroquinolones, inflammation and tendon rupture may develop, particularly in elderly patients and in patients receiving concomitant GCS.

At the first sign of pain or tendon inflammation, patients should stop treatment and relieve the affected limb.

Contraindications

Children and adolescents under 18 years of age, pregnancy, lactation (breast-feeding), hypersensitivity to moxifloxacin.

Use in pregnancy and lactation
Moxifloxacin is contraindicated for use during pregnancy and lactation (breast-feeding).

Application in liver function disorders
Moxifloxacin is prescribed with caution in liver failure.

Application in children
Contraindicated in children and adolescents under 18 years of age.

Use in elderly patients
During therapy with fluoroquinolones, inflammation and tendon rupture may develop in elderly patients. At the first sign of pain or tendon inflammation, patients should discontinue treatment and relieve the affected limb from stress.

Side effects

Digestive system disorders: abdominal pain, nausea, diarrhea, vomiting, dyspepsia, flatulence, constipation, increased liver transaminase activity, perversion of taste.

CNS and peripheral nervous system disorders: dizziness, insomnia, nervousness, anxiety, asthenia, headache, tremor, paresthesia, leg pain, seizures, confusion, depression.

Cardiovascular system: tachycardia, peripheral edema, increased BP, palpitations, chest pain.

Laboratory findings: decreased prothrombin levels, increased amylase activity.

Hematopoietic system disorders: leukopenia, eosinophilia, thrombocytosis, thrombocytopenia, anemia.

Muscular system disorders: back pain, arthralgia, myalgia.

Perior genital system disorders: vaginal candidiasis, vaginitis.

Allergic reactions: rash, itching, urticaria.

.

Similarities