Maxicold Rhino, 15 g 5 pcs.

Pharmacotherapeutic group: remedy for relieving symptoms of acute respiratory infections and “colds” (analgesic non-narcotic + alpha-adrenomimetic + H₁-histamine receptor blocker + vitamin).

ATC code: N02BE51

Pharmacological properties

A combined drug with antipyretic, vasoconstrictor, analgesic and anti-allergic effect.

Paracetamol has antipyretic and analgesic effect: reduces pain syndrome during colds – sore throat, headache, muscle and joint pain, reduces fever.

Pheniramine has antiallergic effect: it eliminates edema and hyperemia of mucous membranes of the nasal cavity, nasopharynx and sinuses, reduces runny nose and lacrimation. Phenylephrine has a vasoconstrictor effect: it reduces nasopharyngeal mucosa edema.

Ascorbic acid (vitamin C) replenishes the increased need for vitamin C during “colds” and flu, especially in the initial stages of the disease, increases resistance to infectious diseases.

The combined effect of pheniramine and phenylephrine reduces nasal congestion and significantly eases nasal breathing.

Indications

Symptomatic treatment of “colds”, ARVI, flu, accompanied by high fever, chills, headache, runny nose, pain in the sinuses and throat, nasal congestion, sneezing and pain in muscles and joints.

Pharmacological effect

Pharmacotherapeutic group: a remedy for eliminating the symptoms of acute respiratory infections and “colds” (analgesic non-narcotic drug + alpha-adrenergic agonist + H1-histamine receptor blocker + vitamin).

ATX code: N02BE51

Pharmacological properties

The combined drug has antipyretic, vasoconstrictor, analgesic and antiallergic effects.

Paracetamol has an antipyretic and analgesic effect: it reduces the pain syndrome observed with “colds” – sore throat, headache, muscle and joint pain, and reduces high temperature.

Pheniramine has an antiallergic effect: eliminates swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses, reduces runny nose and lacrimation. Phenylephrine has a vasoconstrictor effect: it reduces swelling of the nasopharyngeal mucosa.

Ascorbic acid (vitamin C) replenishes the increased need for vitamin C during colds and flu, especially in the initial stages of the disease; increases the body’s resistance to infectious diseases.

The combined action of pheniramine and phenylephrine leads to a reduction in nasal congestion and a significant improvement in nasal breathing.

Special instructions

To avoid toxic liver damage, paracetamol should not be combined with alcoholic beverages, or taken by persons prone to chronic alcohol consumption.

The risk of developing liver damage increases in patients with alcoholic hepatosis.

If the drug is taken by patients suffering from diabetes or on a low-sugar diet, it should be taken into account that each package contains 13599.17 mg of sugar, which corresponds to 1 XE.

Do not use the drug from damaged packages.

Impact on the ability to drive vehicles and machinery

During the period of use of the drug, it is not recommended to drive vehicles and various mechanisms, as well as carry out other potentially dangerous activities that require increased attention and speed of mental and motor reactions.

Active ingredient

Paracetamol, Phenylephrine, Pheniramine, Ascorbic acid

Composition

Active substances:

phenylephrine hydrochloride – 10 mg,

pheniramine maleate – 20 mg,

ascorbic acid – 50 mg,

paracetamol – 325 mg.

Excipients:

Powder for oral solution [lemon]:

citric acid (citric acid anhydrous) – 750.00 mg, malic acid – 7.50 mg, sucrose (sugar) – 13599.17 mg, titanium dioxide – 2.20 mg, sodium citrate (sodium citrate anhydrous) – 123.00 mg, lemon flavor – 52.50 mg, quinoline yellow dye – 0.33 mg, calcium phosphate (tricalcium phosphate) – 60.00 mg, ethylcellulose – 0.30 mg.

Pregnancy

The use of the drug during pregnancy is contraindicated.

If it is necessary to use the drug during breastfeeding, breastfeeding should be discontinued.

Contraindications

Hypersensitivity to individual components of the drug.
Severe renal/liver failure.
Pregnancy.
Breastfeeding period.
Children’s age (up to 12 years).

With caution when:

Arterial hypertension.
Diabetes mellitus.
Angle-closure glaucoma.
Liver or kidney diseases.
Prostatic hyperplasia.
Glucose-6-phosphate dehydrogenase deficiency.

Side Effects

Possible allergic reactions, drowsiness, nausea, epigastric pain, dry mouth, accommodation paresis, increased excitability, dizziness, increased blood pressure, difficulty falling asleep, urinary retention; rarely: anemia.

Interaction

It is recommended to refrain from taking the drug when taking monoamine oxidase inhibitors.

The risk of hepatotoxic action of paracetamol increases with the simultaneous administration of barbiturates, diphenine, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes.

Antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of developing urinary retention, dry mouth, and constipation.

Overdose

Symptoms: nausea, vomiting, pain in the epigastric region; hepatotoxic and nephrotoxic effects; in severe cases, liver failure, encephalopathy and coma develop.

Treatment: you should do a gastric lavage, take activated charcoal and consult a doctor.

Storage conditions

Store at a temperature not exceeding 30 °C.

Shelf life

2 years

Manufacturer

Pharmstandard-Leksredstva, Russia