Mardil Zinc Max solution for external use 1 ml with 5 microcapillaries, 1 pack.

Pharmgroup: Preparation for local treatment of benign skin lesions with cauterizing and mummifying action.

Mardil Zinc® Max is 50% aqueous solution of zinc chlorpropionate and 2-chloropropionic acid. When applied topically and topically to the affected areas of the skin or mucous membranes, the drug is able to interrupt the growth and activity of pathologically changed cells and tissues, including benign neoplasms of the skin and mucous membranes through anticoagulation, dehydration and devitalization. When used on the affected areas the drug leads to fixation with subsequent mummification of pathologically changed tissue with which the drug comes into contact.

The immediate effect of the drug is expressed in discoloration of the skin and mucous membranes with the appearance of a characteristic pale gray hue. Subsequently, the devitalized pathological tissue dries out and changes color to dark brown due to mummification. Mummified scabs detach only after complete reepithelialization spontaneously in 2-3 weeks. Healing proceeds without complications, especially in the absence of secondary infection, leaving no significant scars and scars, deformities of adjacent tissues, or organ dysfunctions.

Pharmacokinetics:

When applied to the affected skin or mucosa, Mardil Zinc® Max is not absorbed and has no systemic effects on the body.

Indications

Effective for:

Composition

How to take, the dosage

For external use

The treatment process is performed on an outpatient basis under the supervision of a physician. The procedure does not require anesthesia. The drug is applied with a plastic spatula, cotton swab or using a glass capillary on the surface of the formation previously degreased with 70% alcohol. Treatment is carried out in 1-3 applications until the appearance of whitish-gray staining. Change of tissue staining occurs within 2-3 minutes after application of the drug. In the presence of pronounced hyperkeratosis within 5-7 minutes. At the same time there is a change in the consistency of the neoplasm to a denser one. The dosage of the drug depends on the type, size, density and severity of hyperkeratosis and may be 0.02 ml-0.2 ml. The maximum daily dose is 0.2 ml.

The number of treatment sessions varies from 1 session (flat warts) up to 3-4 (plantar warts) till the complete disappearance of the element with at least 24 hours interval between the sessions. There is a transient band of hyperemia and edema around the neoplasm after application of Mardil Zinc® Max, which disappears without a trace in 25-40 minutes after the end of the procedure. No additional therapeutic measures are required after application. The day after application the pathological focus mummifies, turns a dark brown color and sharply decreases in size. Mummified scabs detach only after complete epithelialization spontaneously in 2-3 weeks. Healing proceeds without complications, especially in the absence of secondary infection, leaving no significant scars, scars and deformities of adjacent tissues or disruption of organ functions.

For topical use

The treatment of anogenital warts. The treatment is performed as an outpatient procedure under the supervision of a physician and does not require anesthesia. The drug is applied with a universal probe or applicator. After the drug is applied, the color of the tissues changes to a whitish-gray coloration. The amount of the applied drug depends on the size of the formation and the area of the lesion and can be from 0.02 ml to 0.2 ml. During each procedure no more than 2-3 lesion sites with a total area of up to 3 cm2 can be treated. Maximum daily dose is 0.2 ml. If there are more extensive lesions, treatment with the drug should be carried out in several stages with an interval of at least 24 hours. When applying Mardil Zinc® Max a slight swelling of the mucous membrane occurs. Within 2-3 days after using the drug there is detachment of necrotic tissues. Complete regeneration is observed within 10-14 days. With large anogenital warts in the case of incomplete necrosis, it is possible to reapply the drug in 5-7 days.

Interaction

Interaction of the drug Mardil Zinc® Max with other medicinal products of external action has not been established.

Special Instructions

The bottle should be shaken before opening and the solution at the top of the bottle should be moved to the bottom of the bottle. The opened vial should be kept in a strictly vertical position.

Mardil Zinc® Max contains acid. Avoid contact of the product with healthy skin or mucosa. If accidental contact of Mardyl Zinc® Max with healthy skin or mucosa occurs, remove the product as soon as possible using a cotton swab moistened with water.

Particular precautions should be taken when treating affected skin near the eye area. Avoid getting the product into the eyes. If accidental contact of Mardil Zinc® Max into the eyes occurs, rinse immediately with copious amounts of water and 1% sodium bicarbonate solution and then seek medical attention.

The mummified scab should not be removed by scraping or mechanical means. The scab must detach from healthy skin or mucosa on its own, otherwise tissue healing and scarring may be impaired.

Contraindications

Overdose

Erosions may occur if the product is used incorrectly.

In order to prevent acid burns, the product should be rinsed off with running water. Healing can occur on its own without the use of additional medications or with the use of wound healing agents.