Magnelis B6, 120 pcs.
€23.85 €19.88
Pharmacotherapeutic group: Magnesium drug.
ATX code: A12CC01
Pharmacological properties
Compensates for magnesium deficiency.
Magnesium is a vital element that is found in all body tissues and is necessary for normal functioning of cells. It participates in most metabolic reactions, in the regulation of nerve impulse transmission and muscle contraction, has antispasmodic, antiarrhythmic and anti-aggregant effects.
The body gets magnesium with food. Lack of magnesium in the body may be observed in violation of diet (diet) or increased need for magnesium (with increased physical and mental stress, pregnancy, use of diuretics).
Pyridoxine (vitamin B6) is involved in many metabolic processes, in the regulation of metabolism of the nervous system. Vitamin B6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.
The serum magnesium content:
– 12 to 17 mg/L (0.5 to 0.7 mmol/L) indicates moderate magnesium deficiency.
– below 12 mg/L (0.5 mmol/L) indicates severe magnesium deficiency.
Pharmacokinetics
The absorption of magnesium in the gastrointestinal tract is 50% of the oral dose. It is excreted mainly through the kidneys. In the kidneys, after glomerular filtration of 70% of the magnesium present in plasma, it is reabsorbed by the renal tubules in the proportion of 95% – 97%.
Indications
Active ingredient
Composition
Active ingredients
Magnesium lactate dihydrate – 470 mg
In terms of magnesium (Mg2+) – 48 mg
Pyridoxine hydrochloride – 5 mg
Excipients:
Saccharose (white sugar) – 27.4 mg, kaolin – 41.0 mg, acacia gum (gum arabic) – 25.0 mg, collidone SR [polyvinyl acetate 80%, povidone (K 30) 19%, sodium lauryl sulfate 0.8%, silica dioxide 0.2%] – 34.0 mg, magnesium stearate – 6.8 mg, sodium carmellose – 34.0 mg, talc – 6.8 mg.
How to take, the dosage
Consult a doctor before taking this medicine.
Adults are recommended to take 6-8 tablets a day.
Children over 6 years of age (body weight over 20 kg) 4-6 tablets per day.
The full dose should be divided into 2-3 doses, taken with meals, with a glass of water.
The treatment should be stopped after normalization of magnesium concentration in blood.
Interaction
Special Instructions
Information for diabetic patients: The tablets contain sucrose as an excipient.
In case of concomitant calcium deficiency, magnesium deficiency should be eliminated before starting calcium preparations.
In frequent use of laxatives, alcohol, and strenuous physical and mental activity, the need for magnesium increases, which can lead to magnesium deficiency in the body.
Impact on ability to drive vehicles, mechanisms
The drug has no adverse effect on driving and performing potentially hazardous activities requiring increased concentration and quick psychomotor reactions.
Contraindications
Hypersensitivity to the ingredients of the drug, severe renal insufficiency (creatinine clearance less than 30 ml/min), sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.
Children under 6 years of age.
With caution: in moderate renal insufficiency, because there is a risk of hypermagnesemia.
Side effects
Gastrointestinal organs: abdominal pain, constipation, nausea, vomiting, flatulence.
Allergic reactions: allergic reactions to the drug components are possible.
Overdose
In normal renal function, oral administration of magnesium does not cause toxic reactions. Magnesium poisoning may develop in renal failure. Toxic effects depend mainly on the serum magnesium content.
The symptoms of overdose: drop in blood pressure, nausea, vomiting, slowed reflexes, anuria, respiratory depression, coma, cardiac arrest.
Pregnancy use
Pregnancy
Clinical experience has shown no fetotoxic or fetal defects. Magnelis® B6 may be used during pregnancy only by prescription.
Breast-feeding period
Magnesium penetrates into the breast milk. The use of the drug during breastfeeding should be avoided.
Similarities
Weight | 0.152 kg |
---|---|
Shelf life | 3 years. |
Conditions of storage | Temperature not exceeding 25 oC. Keep out of reach of children. |
Manufacturer | Pharmstandard-UfaVITA, Russia |
Medication form | pills |
Brand | Pharmstandard-UfaVITA |
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