Licorice root syrup 100 g

The remedy is of plant origin. Licorice root contains glycyrrhizin (6 to 12%), glycyrrhizic acid and its salts, flavone glycosides (liquiritin, liquiritigenin, liquiritoside), isoflavonoids (formononetin, glabrin, glabridin, glabrol, 3-hydroxyglabrol, glycyrrhizoflavone), coumestane derivatives (glycyrol, isoglycyrol, liquocoumarin), hydroxycoumarins (incl.including gerniarin, umbelliferon, glycocoumarin, lycopyranocoumarin), steroids (sterols, including beta-sitosterol, sigmasterol), essential oils (in small amounts).

Glycyrrhizin stimulates the activity of ciliated epithelium and increases the secretory function of mucous membranes of the upper respiratory tract, facilitates expectoration. It has anti-ulcer and anti-inflammatory effects and reduces platelet aggregation.

The licorice inhibits the enzyme 11-beta-hydroxysteroid dehydrogenase in the kidneys, which leads to a decrease in the conversion of cortisol into cortisone. The mineralocorticoid activity of cortisol is due to a decrease in serum potassium concentration and an increase in sodium, which leads to fluid retention in the body, an increase in body weight and arterial hypertension. Glycyrrhizic acid and its metabolites inhibit peripheral cortisol metabolism and cause a pseudoaldosterone-like effect.

Liquiritoside has an antispasmodic effect on smooth muscles.

Indications

Diseases of the upper respiratory tract, lungs; hyperacid gastritis, gastric ulcer and duodenal ulcer. Addison’s disease, hypofunction of the adrenal cortex (in the complex therapy).

Active ingredient

Composition

100 ml of syrup contain:

The active ingredients:

liquorice root extract dense 4 g,

sugar syrup 86 g,

ethyl alcohol 96% and water to 100 ml.

How to take, the dosage

Licorice root syrup is taken orally, adults 1 dessert spoon in 1/2 cup of water 3 times a day.

Children under 2 years of age take as many drops as the child has several times a day, 2-12 years – 1/2 teaspoon in 1/4 cup of water, over 12 years – 1 teaspoon 3 times a day, the course duration is 7-10 days.

Interaction

The simultaneous use of thiazide diuretics with licorice is not recommended because of the risk of hypokalemia.

Hypokalemia due to long-term use of licorice may potentiate the toxic effects of cardiac glycosides.

The simultaneous use of licorice and GCS may increase the half-life of cortisol.

Special Instructions

When prescribed to patients with bronchial asthma, continuous monitoring is required (intolerance reactions are possible).

Contraindications

With caution: liver disease, alcoholism, brain injury, brain disease, diabetes, children.

Side effects

Nausea, heartburn, allergic reactions.

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