Libexin Muco, 50 mg/ml syrup 125 ml

Carbocysteine, being a mucolytic, acts on the gel phase of the endobronchial secretion, breaking disulfide bridges of glycoproteins and thus reducing viscosity and increasing elasticity of the secretion.

Carbocysteine activates sialic acid transferase – an enzyme of bocalytic cells of the bronchial mucosa, normalizes the quantitative ratio of acidic and neutral sialomucins, promotes mucous membrane regeneration, normalizes its structure, stimulates the activity of ciliated epithelium, restores the secretion of immunologically active IgA (specific protection), improves mucociliary clearance.

Pharmacokinetics

Carbocysteine is rapidly absorbed after oral administration, reaching maximum serum levels after 2 hours. Bioavailability is low (less than 10% of the dose taken) as a result of possible rapid passage through the liver. The elimination half-life is about 2 hours. It is excreted mainly by the kidneys together with the metabolites.

Indications

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