Lamisil, cream 1% 30 g

Antifungal drug for external use, which has a broad spectrum of antifungal activity. In low concentrations, terbinafine has fungicidal activity against dermatophytes (Trychophyton rubrum, Trychophyton mentagrophytes, Trychophyton verrucosum, Trychophyton violaceum, Trychophyton tonsurans, Microsporum canis, Epidermophyton floccosum), molds (mainly Candida albicans) and some dimorphs (Pityrosporum orbiculare). Activity against yeast fungi, depending on their species, may be fungicidal or fungistatic.

Terbinafine specifically changes the early stage of sterol biosynthesis occurring in fungi. This leads to ergosterol deficiency and intracellular accumulation of squalene, which causes cell death of the fungus.

Indications

Active ingredient

Composition

The active ingredient:

terbinafine hydrochloride 10 mg;

Associates:

benzyl alcohol;

sodium hydroxide;

How to take, the dosage

Interaction

Directions for use

Special Instructions

Synopsis

Contraindications

Side effects

Definition of side effect frequency (WHO): very common (≥1/10), common (≥1/100 and < 1/10), infrequent (≥1/1000 and < 1/100), rare (≥1/10 000 and < 1/1000), very rare (< 1/10 000), including individual reports.

Immune system: isolated reports – hypersensitivity reactions (rash).

Visually: rare – eye irritation.

Skin: often – skin peeling, itching; infrequent – skin damage, crusting, skin lesions, pigmentation disorders, erythema, burning sensation of the skin; rarely – feeling of dry skin, contact dermatitis, eczema; single reports – rash.

Local reactions: infrequent – pain, pain at the application site, irritation at the application site; rarely – exacerbation of disease symptoms. Itching, peeling of the skin, painful sensations, irritation, changes in skin pigmentation, burning, erythema and crusts may be observed where the drug is applied.

These minor symptoms should be distinguished from hypersensitivity reactions, such as rash, which occur in rare cases and require discontinuation of therapy. In rare cases, the course of the fungal infection may worsen.

If any of these side effects worsen, or if the patient notices any other side effects, you should tell your doctor.

Overdose

Pregnancy use

Similarities