Ketoconazole DC, tablets 200 mg 10 pcs
€7.83 €6.85
Ketoconazole DC is an antifungal agent and is active against dermatophytes, yeasts, dimorphic fungi and eumycetes.
It is also active against staphylococci and streptococci.
The mechanism of action is to inhibit the synthesis of ergosterol of fungi.
Prevents the transformation of Candida albicans blastospores into invasive forms.
Indications
Used to treat the following diseases:
dermatophytosis, onychomycosis caused by blastomycetes, hyphomycetes;
vaginal candidiasis, mucocutaneous candidiasis, lichen versicolor;
systemic mycoses;
mycoses of the gastrointestinal tract and genitourinary system;
for the prevention of mycoses in patients with reduced immunological resistance of the body.
Pharmacological effect
Ketoconazole DS is an antifungal agent that is active against dermatophytes, yeasts, dimorphic fungi and eumycetes.
Also active against staphylococci and streptococci.
The mechanism of action is to inhibit the synthesis of fungal ergosterol.
Prevents the transformation of Candida albicans blastospores into invasive forms.
Special instructions
With long-term use, it is necessary to monitor the condition of the liver.
If liver disease occurs, the drug should be stopped.
Use with caution in children: long-term use inhibits cortisol synthesis and vitamin D metabolism.
Active ingredient
Ketoconazole
Composition
1 tablet contains:
active ingredient:
ketoconazole 200 mg,
excipients:
lactose 40 mg,
corn starch 25 mg,
pregelatinized starch 12 mg,
microcrystalline cellulose 7.5 mg,
polyvinylpyrrolidone 12.5 mg,
magnesium stearate 5 mg,
sodium starch glycolate 10 mg
Contraindications
Individual intolerance to the components of the drug.
Pregnancy and lactation period.
Patients with acute or chronic liver diseases.
Side Effects
Temporary decrease in plasma testosterone levels.
In rare cases, nausea, constipation, stomach pain, flatulence, gastrointestinal bleeding, diarrhea, headache, and dizziness occur.
Interaction
With simultaneous use of ketoconazole with rifampicin and isoniazid, a decrease in the concentration of ketoconazole in the blood plasma is observed.
With simultaneous use of ketoconazole with cyclosporine, indirect anticoagulants and methylprednisolone, their concentrations in the blood plasma may increase.
Storage conditions
In a dry place, protected from light, at a temperature below 25 °C
Shelf life
3 years
Manufacturer
ZiO-Zdorovye CJSC, Russia
Shelf life | 3 years |
---|---|
Conditions of storage | In a dry, light-protected place at a temperature below 25 °C |
Manufacturer | ZiO-Zdorovye CJSC, Russia |
Medication form | pills |
Brand | ZiO-Zdorovye CJSC |
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