Humalog Mix 25, 100 me/ml suspension 3 ml quikpen syringe pen cartridges 5 pcs

Hypoglycemic drug, a combination of fast- and medium-acting insulin analogues. Humalog^® Mix 25 is a DNA recombinant human insulin analog and is a ready-mix consisting of a solution of insulin lispro (a fast-acting human insulin analog) and an insulin lispro protamine suspension (a medium-acting human insulin analog).

The main action of lispro insulin is to regulate glucose metabolism. In addition, it has anabolic and anti-catabolic effects on various tissues of the body. In muscle tissue there is an increase of glycogen, fatty acids, glycerol, increased protein synthesis and increased consumption of amino acids, but there is a decrease of glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism and release of amino acids.

Lispro insulin has been shown to be equimolar to human insulin, but its action is faster and lasts for a shorter time. It has an onset of action about 15 minutes later than normal human insulin and could be injected immediately before a meal (0-15 minutes before the meal). After Humalog Mix 25 injection, there is a rapid onset of action and early reaching the peak of insulin lispro activity. The action profile of insulin lispro protamine is similar to that of regular isophan insulin with a duration of action of approximately 15 hours.

Indications

Active ingredient

How to take, the dosage

Interaction

Special Instructions

Contraindications

Side effects

A side effect associated with the main effect of the drug: the most common is hypoglycemia. Severe hypoglycemia can lead to loss of consciousness and, in exceptional cases, to death.

Allergic reactions: Local allergic reactions are possible – redness, swelling or itching at the injection site (usually disappear within a few days or weeks; in some cases, these reactions may be caused by causes unrelated to insulin, such as skin irritation with antiseptic or improper administration of injections); systemic allergic reactions (occur less frequently, but are more serious) – generalized itching, difficulty breathing, shortness of breath, BP decrease, tachycardia, increased sweating. Severe cases of systemic allergic reactions can be life-threatening.

In rare cases of severe allergy to Humalog Mix 25, immediate treatment is required. A change of insulin or desensitization may be necessary.

Local reactions: with prolonged use, lipodystrophy may develop at the injection site.

Overdose

Similarities