Herperax, ointment 5% 5 g

Antiviral agent for external use, synthetic analog of purine nucleoside. Thymidine kinase of virus-infected cells actively converts acyclovir through a series of sequential reactions into acyclovir mono-, di- and triphosphate.

Indications

Treatment of skin infections caused by Herpes simplex viruses types 1 and 2, including primary and recurrent genital herpes as well as herpes localized on the lips.

Active ingredient

Composition

Acyclovir 5.75 g

Supplementary substances:

Polyethylene glycol 4000,

Polyethylene glycol 1500,

Polyethylene glycol 400.

How to take, the dosage

Externally. Apply 4-6 times/day (every 4 hours) in a thin layer on the affected and adjacent skin areas. The drug is applied either with a cotton swab or clean hands to avoid additional infection of the affected areas. The therapy should be continued until the blisters have crusted over, or until they are completely healed. The duration of therapy is an average of 5 days and should not exceed 10 days.

It is important to start treatment of recurrent infection during the prodromal phase or at the beginning of the manifestation of the infection.

The duration of treatment is at least 5 days. If there is no healing, treatment may be continued for up to 10 days. If symptoms persist for more than 10 days, a physician should be consulted.

Interaction

When used topically in the recommended doses, no systemic interaction of Herperax ointment with other drugs was found.

Special Instructions

Herperax ointment should not be applied to the mucous membranes of the mouth, eyes, nose and vagina. The effectiveness of treatment will be the higher the earlier it is started (at the first signs of infection).

Contraindications

Side effects

Definition of the frequency of adverse reactions: very frequently (≥1/10), frequently (≥1/100, <1/10), infrequently (≥1/1000, <1/100), rarely (≥1/10 000, <1/1000) and very rarely (<10 000), frequency unknown (frequency of occurrence cannot be determined based on available data).

Local reactions: infrequent – possible burning sensation at the application site, which eventually subsides, dry skin, itching; rarely – erythema, contact dermatitis at the application site. In contact with the mucous membranes may cause inflammation.

The immune system: very rare – anaphylactic reactions, including angioedema and urticaria.

Overdose

Symptoms (in case of accidental ingestion): headache, neurological disorders, shortness of breath, nausea, vomiting, diarrhea, impaired renal function, lethargy, seizures, coma.

Treatment: maintenance of vital functions, hemodialysis.

Pregnancy use

The use of acyclovir during pregnancy is possible in cases when the estimated benefit to the mother exceeds the potential risk to the fetus.

If it is necessary to use during lactation, discontinuation of breastfeeding should be considered.

Similarities