Heptral, 500 mg 20 pcs.

Indications

Active ingredient

Composition

How to take, the dosage

Depression

The therapy with Heptral® may be initiated by intravenous or intramuscular injection followed by administration of Heptral® tablets or directly with Heptral® tablets.

Patients in elderly patients:

Clinical experience with Heptral® has not shown any difference in efficacy between elderly patients and younger patients. However, taking into account high possibility of existing hepatic, renal or cardiac impairment, other comorbidities or concomitant therapy with other medicinal products, the dosage of Heptral® should be adjusted with caution in elderly patients starting from the lowest dose range.

Renal Impairment:

There are limited clinical data available on the use of Heptral® in patients with renal impairment; therefore, caution is recommended when using Heptral® in these patients.

Hepatic failure:

The pharmacokinetic parameters of ademetionine are similar in healthy volunteers and in patients with chronic liver disease.

Children:

The use of the drug Heptral® in children is contraindicated (efficacy and safety have not been established).

Interaction

Special Instructions

Influence on the ability to drive and operate machinery

In some patients dizziness may occur while taking Heptral®. It is not recommended to drive a vehicle or operate machinery while taking this medicine until the patient is sure that the therapy does not affect the ability to perform this type of activity.

Synopsis

Contraindications

Pregnancy (first trimester) and the period of breastfeeding (use is possible only if the potential benefit to the mother exceeds the possible risk to the fetus or baby).

Simultaneous use with selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (such as clomipramine), and herbal and tryptophan preparations.

Elderly age.

Renal insufficiency.

Side effects

Overdose

Pregnancy use

Similarities