Hemodez-N, 400 ml

The action of the drug is due to the ability of low-molecular polyvinylpyrrolidone to bind toxins circulating in blood and quickly remove them from the body. It most completely binds toxins circulating in the blood of patients with dysentery, salmonellosis, food intoxications. In burn disease toxins formed during the first 4-5 days of the disease are almost completely inactivated; toxins formed in later periods are much weaker neutralized.

Toxins produced in patients during acute radiation disease are not bound, although it is possible to accelerate their removal from the body.

The drug helps eliminate stasis of red blood cells in the capillaries, developing in intoxication of any origin, which leads to improved microcirculation. It enhances renal blood flow, increases glomerular filtration and increases diuresis. The drug is non-toxic and has no antigenic and pyrogenic properties. The reduction of the molecular weight of the polymer accelerates its excretion by the kidneys and improves the detoxification properties of the drug.

Pharmacokinetics

It is not metabolized in the body. It is rapidly excreted by the kidneys, within 4 hours – 80%, after 12-24 hours – completely.

Indications

– shock (post-traumatic, post-operative, burn, hemorrhagic);

– intoxication (toxic gastrointestinal diseases, including. dysentery, dyspepsia, salmonellosis; burn, radiation and hemolytic disease, peritonitis, intestinal obstruction, thyrotoxicosis, liver disease, sepsis, pneumonia; acute phase of myocardial infarction);

– neonatal toxemia;

– gestosis.

Active ingredient

Composition

povidone (polyvinylpyrrolidone) low molecular weight medical with molecular weight 8000±2000 6 g

sodium chloride 550 mg

potassium chloride 42 mg/p>

calcium chloride 50 mg

sodium hydrocarbonate 23 mg

magnesium chloride anhydrous 500 µg

Excipients: water d/i.

How to take, the dosage

In/vitro drip (40-80 drops/minute), through a device with a filter and polymer needle for connection to the container.

The dose depends on the age of the patient and the severity of intoxication.

The single dose for adults is 200-500 ml; for children – 5-10 ml/kg; maximum single dose for infants is 50-70 ml, for 2-5 year olds – 100 ml, 5-10 year olds – 150 ml, 10-15 year olds – 200 ml. The drug is administered once or up to two times a day for 1 to 10 days depending on the severity of intoxication.

In case of acute gastrointestinal infections, burns and radiation sickness it is administered 1-2 times a day; in case of hemolytic disease and toxemia in newborns – 2-8 times a day (daily or every other day); in case of myocardial infarction (in the 1st day) – 200 ml once, in complications on the 2nd day – 200 ml.

Special Instructions

In case of extensive burns it is combined with the administration of plasma, albumin, gamma-globulin.

Before starting the infusion it is necessary to check the expiration date of the package. The drug must be transparent, free of suspended solids, sediment and mold. Pressing on the container with the drug checks its tightness and integrity of the package. The results of visual inspection are recorded in the case history. In the course of treatment it is necessary to monitor the BP and the patient’s condition.

The solution is heated to body temperature before injection.

Contraindications

– intracranial hypertension;

– hemorrhagic stroke;

– condition after craniocerebral trauma;

– chronic heart failure II-III stage.

– respiratory failure;

– severe allergic reactions;

– thromboembolism;

– oliguria, anuria, acute nephritis;

– bronchial asthma;

– phlebothrombosis;

– hypersensitivity.

Side effects

Pressure decrease, tachycardia, difficulty of breathing (during rapid infusion), allergic reactions of varying severity (up to the development of anaphylactic shock). Infection at the injection site, thrombosis or phlebitis, spreading from the place of infusion.

Similarities