Helmintox, 250 mg 3 pcs.

Pharmgroup: < br>

anthelminthic drug.

Pharmic action:

Helminthox is an antihelminthic drug. Causes neuromuscular blockade of sensitive helminthes and ensures their expulsion from the gastrointestinal tract without excitation and stimulation of migration of the affected helminthes. In the intestinal lumen it is effective against mature and immature sensitive helminthes of both sexes.

Highly effective against infestations caused by pinworms (Enterobius vermicularis), ascarias (Ascaris lumbricoides), ankylostomas (Ankylostoma duodenale and Necator americanus).

Pharmacokinetics: < br>

Intake
Practically not absorbed from the gastrointestinal tract. After a single dose of 12.5 mg/kg body weight, the plasma concentration of pyrantel is 0.05-0.13 µg/ml for 1-3 hours.

Metabolism and excretion
Partially metabolized in the liver to K-methyl-1,3-propanediamine.

Extracted through the intestine (about 93%) unchanged, by the kidneys (7%) – unchanged or as a metabolite.

Indications

Active ingredient

Composition

1 tablet contains:

Active ingredient:

Pyrantel embonate;

Associates:

corn starch,

sodium starch glycolate,

magnesium stearate,

methylhydroxypropylcellulose,

polyethylene glycol 400 monostearate,

propylene glycol,

titanium dioxide,

the yellow-orange dye on aluminum oxide varnish.

How to take, the dosage

Over the mouth, at any time of the day, without taking laxatives beforehand, not necessarily on an empty stomach.

The tablets are intended for adults and children over 6 years of age.

In children under 6 years of age, only the suspension is recommended. The suspension is intended for children weighing more than 12 kg. Shake the suspension before use.

1 ml of the suspension contains 50 mg of pyrantel base, 1 scoop (2.5 ml) contains 125 mg of pyrantel base.

A pinworms and ascarids: in the treatment of enterobiasis and ascariasis the drug is prescribed once in the recommended dose.

The usual dosage is 12.5 mg/kg once:

To prevent re-infection, repeat taking the drug after 3 weeks.

Ankylostomas: in endemic areas, in case of Necator americanus infection or severeAnkylostoma duodenale infection, 25 mg/kg/day (in 1 or 2 doses) for 2-3 days:

In case of infection with Ankylostoma duodenale outside of endemic areas (runs more easily) – at a dose of 12.5 mg/kg in 1 dose.

Special Instructions

An existing liver disease should be reported to your doctor.

Contraindications

Cautiously: the drug should be administered in children under 6 months of age.

Side effects

Digestive system disorders: sometimes – nausea, vomiting, abdominal pain, diarrhea, loss of appetite (most often these symptoms are caused by death of helminths), slight transient increase in liver transaminase activity.

CNS and peripheral nervous system disorders: headache, dizziness, feeling of fatigue, drowsiness or insomnia, hearing disorders, hallucinations, confusion, paresthesias.

Allergic reactions: itching, urticaria, exanthema.

Others: hyperthermia.

Pregnancy use

In pregnancy Helmintox should be used in case of extreme necessity. Breastfeeding should be stopped during the treatment (the drug penetrates into the mother’s milk).

Similarities