Halixol, tablets 30 mg 20 pcs

An expectorant (mucolytic) drug. Ambroxol is the active metabolite of bromhexine, belongs to the benzylamine group of mucolytic substances.

Thickens sputum by increasing the production and activity of hydrolytic enzymes which break the bonds between mucopolysaccharides of sputum.

It improves rheological properties of sputum by reducing its viscosity and adhesive properties due to stimulation of serous cells of the bronchial mucous membrane glands and normalization of the ratio of the mucous and serous components of sputum.

increases mucociliary transport by increasing the motor activity of the atrial epithelium. It does not cause excessive secretion and reduces spastic bronchial hyperresponsiveness.

Promotes the production of surfactant.

The effect occurs within 30 minutes after taking the drug.

Indications

Active ingredient

Composition

1 tablet contains:

The active ingredient:

ambroxol hydrochloride 30 mg;

Associates:

Lactose monohydrate – 84 mg;

MCC – 30 mg;

povidone K30 – 5 mg;

sodium carboxymethyl starch (type A) – 10 mg;

magnesium stearate – 1 mg.

How to take, the dosage

Chalixol is taken orally, after meals, with plenty of fluids (plenty of fluids helps to thin mucus during treatment with ambroxol). The syrup can be taken with a measuring cup.

Adults and children over 12 years of age – usual daily dose in the first 2-3 days of treatment: 1 tablet 3 times a day, in the next days – 1 tablet 2 times or 1/2 tablet 3 times a day. In severe cases the dose is not reduced during the entire course of treatment.

Chalixol syrup is recommended for children under 5 years of age.

Children between 5 and 12 years of age take 1/2 tablet 2 to 3 times a day.

Interaction

Anticough drugs (including codeine) may make it difficult to excrete sputum liquefied by ambroxol.

Halixol® promotes penetration into the bronchial secretion of some antibiotics (including amoxicillin, cefuroxime, erythromycin, doxycycline).

Special Instructions

Should not be administered concomitantly with anti-cough drugs because of difficulties in sputum secretion.

The use of the drug in patients with impaired bronchial motor function or abundant sputum production with low viscosity requires caution due to the risk of bronchial stasis.

The syrup contains nonspecific sweeteners, sorbitol, and sodium cyclamate; therefore, patients with diabetes may use this product, but the sorbitol content (1.2 g per 5 ml) must be taken into consideration by patients with diabetes.

The product does not contain alcohol.

Contraindications

The drug should be used with caution in severe renal failure.

Side effects

CNS disorders: rarely – weakness, headache.

The digestive system: rarely – diarrhea, constipation, dry mouth, gastralgia, nausea, vomiting.

Respiratory system disorders: rarely – dry airways, rhinorrhea.

Allergic reactions: rarely – exanthema, urticaria; extremely rare – acute anaphylactic reactions, the causal connection of which with the use of ambroxol is not determined.

Others: dysuria.

Overdose

Symptoms: nausea, vomiting, diarrhea, dyspepsia.

Treatment: induce vomiting, then prescribe drinking (milk or tea), taking fat-containing products. Gastric lavage is recommended within 1 -2 h after taking the drug. The function of the cardiovascular system should be monitored continuously.

Pregnancy use

The drug is contraindicated for use in the first trimester of pregnancy.

Ambroxol is excreted with the breast milk, so if it is necessary to use the drug during lactation, the question of stopping breastfeeding should be addressed.

Similarities