Glutargin alcocline, 1 g tablets 2 pcs

Glutargin is a salt of arginine and glutamic acid. During alcohol intoxication it stimulates alcohol utilization in monooxygenase system of the liver, prevents inhibition of the key enzyme of ethanol utilization – alcohol dehydrogenase; accelerates inactivation and excretion of toxic products of ethanol metabolism by increasing formation and oxidation of succinic acid; reduces depressant effect of alcohol on CNS due to neurotransmitter properties of excitatory glutamic acid. Due to these properties Glutargin shows antitoxic and sobering effects.

Glutargin also possesses hypoammonemic and hepatoprotective properties due to the activation of ammonia detoxification processes in the body, antioxidant, antihypoxic and membrane stabilizing effects and has a positive effect on energy supply processes in hepatocytes.

Glutargin does not have embryotoxic, gonadotoxic, mutagenic and teratogenic effects and does not cause allergic and immunotoxic reactions.

Indications

Prevention of intoxication and hepatoxic effects of alcohol. Treatment of acute alcohol intoxication and moderate degree of severity, as well as in the complex therapy of post intoxication disorders after acute alcohol poisoning of severe degree.

Active ingredient

Composition

Tablets.

Active ingredient:

Arginine glutamate (in terms of 100% substance) 1.0 g.

Auxiliary ingredient:

Microcrystalline cellulose (MCC 101) 0, 110 g,

crospovidone 0.020 g,

calcium stearate 0.010 g.

How to take, the dosage

The drug is prescribed to adults orally, regardless of meals.

In order to prevent intoxication and hepatotoxic effect of alcohol the drug is prescribed 2 tablets (2 g arginine glutamate) 1-2 hours before alcohol intake or 1 tablet (1 g arginine glutamate) 1 hour before alcohol intake and 1 tablet (1 g arginine glutamate) within 0.5 hours after alcohol intake.

Special Instructions

When prescribing to patients with endocrine dysfunction, it should be noted that the drug may slightly increase insulin and growth hormone secretion, which does not require correction of drug therapy in patients with diabetes and/or acromegaly./p>

The effect of the drug on driving ability

The drug does not affect driving ability

Contraindications

– hypersensitivity to the components of the drug

– childhood under 18 years

– pregnancy and lactation

With caution

– febrile condition

– hypersensitivity

– severe impairment of filtration (nitrogen-excretory) renal function (creatinine clearance 30 ml/min).

Side effects

Slight discomfort in the epigastric region and nausea immediately after using the drug may rarely occur, but it clears on its own.

Overdose

Symptoms: nausea, vomiting, pain in the chest area, discomfort in the epigastric region, insomnia, transient transient decrease of blood pressure, atrioventricular block, allergic reactions.

Treatment: symptomatic, if necessary antihistamines, in severe cases – intravenous administration of glucocorticosteroids.