Gastal, tablets 30 pcs.
€11.20 €9.34
Reflux esophagitis, Sour belching, Peptic ulcer, Heartburn, Chronic pancreatitis, Gastritis
- Dyspeptic phenomena such as discomfort or pain in epigastrium, heartburn, sour belching after errors in diet, excessive use of ethanol, coffee, nicotine, etc.
- dyspeptic phenomena, such as discomfort or pain in the epigastrium, heartburn, sour belching (and their prevention), arising from the use of certain drugs (nonsteroidal anti-inflammatory drugs, glucocorticosteroids, etc.).
- conditions accompanied by increased acid generation: gastric ulcer, gastritis, reflux esophagitis; hernia of the esophageal orifice of the diaphragm.
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Indications
Dyspeptic symptoms, such as discomfort or pain in the epigastrium, heartburn, sour belching after errors in diet, excessive consumption of ethanol, coffee, nicotine, etc.;
dyspepsia, such as discomfort or pain in the epigastrium, heartburn, sour belching (and their prevention), resulting from the use of certain medications (non-steroidal anti-inflammatory drugs, glucocorticosteroids, etc.);
conditions accompanied by increased acid formation: gastric ulcer, gastritis, reflux esophagitis; hiatal hernia.
Pharmacological effect
Pharmacological group:
Special instructions
Reduced doses and a shortened treatment period are indicated for adults with reduced weight (less than 50 kg) and children.
The recommended dose and duration of treatment should not be exceeded when used in patients with impaired renal function.
Continuous use for more than 2 weeks is possible only after consulting a doctor.
Impact on the ability to drive a car or perform work that requires increased speed of physical and mental reactions. The use of the drug Gastal® does not affect the ability to drive vehicles or control other mechanisms.
Active ingredient
Aluminum hydroxide-magnesium carbonate, magnesium hydroxide
Composition
1 tablet contains:
Contraindications
Hypersensitivity to aluminum, magnesium salts or other components of the drug;
severe renal failure;
Alzheimer’s disease;
hypophosphatemia;
lactose intolerance, lactase deficiency or glucose-galactose malabsorption;
children under 6 years of age.
With caution: in case of chronic renal failure (CRF), pregnancy and during breastfeeding, adults and children over 12 years old weighing less than 50 kg, children from 6 to 12 years old, elderly people.
Side Effects
When using the drug in recommended doses, adverse reactions are rare (not less than 0.01%, but less than 0.1%): nausea, constipation, diarrhea, changes in taste.
In exceptional cases, allergic reactions are possible.
Interaction
The drug Gastal®, when used simultaneously, enhances the activity of levodopa and nalidixic acid, reduces and slows down the absorption of quinolones, isoniazid, naproxen, iron preparations, indomethacin, aminazine, beta-blockers, diflunisal, H2-histamine receptor blockers, fat-soluble vitamins, indirect anticoagulants, barbiturates.
When interacting with metal ions included in antacids, tetracyclines form insoluble chelate complexes; as a result of this interaction, the absorption of tetracyclines is reduced by more than 90%. The simultaneous use of these drugs is not possible. If combined use is necessary, tetracycline should be taken at least 2 hours before taking the antacid.
In the presence of aluminum and magnesium hydroxides contained in the antacid, the absorption of ciprofloxacin and ofloxacin is reduced by 50-90%.
In the presence of antacids, the bioavailability of captopril is significantly reduced, and the combined use of antacids and metoprolol leads to a decrease in the concentration of metoprolol in the blood plasma.
Concomitant use of high doses of antacids can reduce the absorption of ranitidine by 10-33%.
The use of antacids does not affect the bioavailability of amoxicillin, cephalexin and the combination of amoxicillin and clavulanic acid, but can significantly reduce the absorption of doxycycline from the gastrointestinal tract.
An increase in urine pH during antacid therapy may increase the tubular reabsorption of basic (alkaline) drugs and reduce the reabsorption of acidic compounds. Antacids can reduce and slow down the absorption of salicylates, including acetylsalicylic acid, and also, by increasing the pH of urine, promote faster excretion of salicylates in the urine from the body, with a concomitant decrease in their concentration in the blood serum by 30-70%.
The absorption of cardiac glycosides, including digoxin and digitoxin, is not significantly reduced when used simultaneously with antacids.
M-anticholinergic blockers, by slowing down gastric motility, increase the duration of action of the drug Gastal®.
In order to prevent possible interaction of the drug Gastal® with other drugs, it is recommended to take it 1 hour before or 1 hour after their use.
Overdose
Symptoms of acute overdose are not described.
With long-term use of high doses of drugs containing aluminum and magnesium, the development of hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis and impaired renal function is possible. It is possible to develop more pronounced adverse reactions from the gastrointestinal tract (GIT) (constipation, diarrhea), in patients with renal failure – thirst, decreased blood pressure, hyporeflexia.
Treatment: symptomatic therapy.
Storage conditions
Store at a temperature not exceeding 25 ºС.
Keep out of the reach of children.
Shelf life
3 years
Manufacturer
Teva Operations Poland Sp. z o.o., Poland
Shelf life | 3 years |
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Conditions of storage | Store at a temperature not exceeding 25 ºC. Store out of the reach of children. |
Manufacturer | Teva Operations Poland Sp. z o.o., Poland |
Medication form | lozenges |
Brand | Teva Operations Poland Sp. z o.o. |
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