Gastal, mint tablets 12 pcs.

Interaction

Tell your doctor or pharmacy technician if you are taking, have recently taken, or might start taking any other medicines.

Gastal^® when taken concomitantly, increases the activity of levodopa and nalidixic acid and decreases and slows down the intestinal absorption of quinolones, isoniazid, naproxen, iron drugs, indomethacin, aminazine, beta-adrenal blockers, diflunisal, Hsub>2-histamine receptors, fat-soluble vitamins, indirect anticoagulants, barbiturates.

In interaction with metal ions from antacids, tetracyclines form insoluble chelate complexes; as a result of this interaction the absorption of tetracyclines is reduced by more than 90%. Simultaneous administration of these drugs is not possible. If simultaneous use is necessary, tetracycline should be taken at least 2 hours before taking the antacid.

In the presence of aluminum and magnesium hydroxides contained in the antacid, absorption of ciprofloxacin and ofloxacin is reduced by 50-90%.

In the presence of antacids, blood absorption of captopril is significantly reduced, and concomitant use of antacids and metoprolol leads to decreased plasma concentrations of metoprolol.

The concomitant use of high doses of antacids may reduce the absorption of ranitidine by 10-33%.

The use of antacids does not affect the proportion of amoxicillin, cephalexin and the combination of amoxicillin and clavulanic acid that enters the blood after taking these drugs, but may significantly reduce the absorption of doxycycline from the gastrointestinal tract.

Elevated urinary pH on antacid therapy may increase tubular reabsorption of basic (alkaline) drugs and decrease reabsorption of acidic compounds. Antacids may decrease and slow down absorption in the intestine of salicylates, including acetylsalicylic acid, and by increasing the urinary pH, contribute to more rapid urinary excretion of salicylates from the body, with an accompanying decrease in their concentration in serum by 30-70%.

The absorption of cardiac glycosides, including digoxin and digitoxin, when used concomitantly with antacids is not significantly reduced.

M-cholinoblockers, by slowing gastric motility, increase the duration of action of the drug Gastal^®.

In order to prevent possible interaction of the drug Gastal^® with other medicinal products it is recommended to take it 1 hour before or 1 hour after their use.

Special Instructions

Consult with your doctor or pharmacist before taking Gastal^® .

The recommended doses and duration of treatment should not be exceeded when used in patients with impaired renal function.

In young children, use of magnesium hydroxide may result in elevated magnesium levels in the body, especially if they have severe kidney disease or dehydration.

Children and adolescents

The drug Gastal^® is not intended for use in children under 6 years of age.

Driving and operating machinery

The use of the drug Gastal ^® does not affect the ability to drive vehicles and operate other machinery.

Gastal^® Contains lactose monohydrate

If you have an intolerance to some sugars, talk to your doctor before taking this medicine.

Synopsis

– Gastal®, a snack tablet [mint, cherry and orange], is an antacid – a medicine that directly binds the acid that has already been excreted in the stomach and thus reduces the high acidity of the gastric juice. It reduces the acidity of gastric juice, protecting the mucous membrane of the esophagus, stomach and duodenum from its action. The drug is used for short-term relief of symptoms of high acidity in the stomach (e.g., discomfort or pain in the stomach area due to the use of certain medications or errors in diet), symptoms of abnormal discharge of stomach contents into the esophagus (which may appear as burning sensation behind the chest, i.e.
– Gastal® is a rapid-acting drug, and its therapeutic activity lasts for up to 2 hours.

Contraindications

– allergy to salts of aluminum, magnesium or any other components of the drug (listed in Section 6 of the package insert);
– severe renal impairment, which is usually manifested by a significant increase in blood creatinine level and is called severe renal failure;
– Alzheimer’s disease;
– decreased concentration of phosphate in blood;
– lactose intolerance, lactase enzyme deficiency in intestinal mucosa, glucose-galactose malabsorption (rare genetically conditioned disorder of glucose and galactose sugars absorption in intestine);
– children under 6 years old.

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Side effects

Like all medications, this medication can cause adverse reactions, but not everyone has them.

Stop taking the drug in case of nausea, diarrhea, constipation, elevated magnesium levels in the body, or seek immediate medical attention in case of allergic reactions and abdominal pain.

Summary of adverse reactions

Rarely (not more than 1 person in 1,000) – nausea, diarrhea, constipation.

Very rare (may occur in no more than 1 person in 10,000) – allergic reactions, elevated magnesium levels in the body (seen after long-term use of magnesium hydroxide in patients with renal insufficiency).

Frequency is unknown (based on available data, the frequency of occurrence cannot be determined) – abdominal pain.

Overdose

Symptoms of acute overdose are not described.

Pregnancy use

If you are pregnant or breastfeeding, think you may be pregnant, or are planning a pregnancy, talk to your doctor or pharmacist before using this medicine.

Pregnancy
If used during pregnancy and while breastfeeding, the balance of benefit to the mother and risk to the fetus and infant must be assessed. The drug should be used during pregnancy only if necessary and only on the doctor’s recommendation.

Breastfeeding
The drug Gastal® is not excreted with the breast milk.