Furasol, 100 mg 1 g 15 pcs

Furasol is an antimicrobial agent, a nitrofuran derivative. It is effective against Gram-positive cocci (Staphylococcus spp., Streptococcus spp.), Gram-negative bacilli (E. coli, Salmonella spp., Shigella spp., Klebsiella spp.). Resistant: Acinetobacter spp., most strains of Proteus spp., Serratia spp.

The mechanism of action is associated with inhibition of nucleic acid synthesis. Depending on concentration it has bactericidal or bacteriostatic action.

Against most bacteria the bacteriostatic concentration is 10-20 µg/ml. Bactericidal concentration is about 2 times higher.

Under the influence of nitrofurans in microorganisms there is inhibition of respiratory chain activity and tricarboxylic acid cycle (Krebs cycle) as well as inhibition of other biochemical processes, which leads to destruction of their envelope or cytoplasmic membrane. Nitrofurans increase complement titer and the ability of leukocytes to phagocytize microorganisms.

Indications

As a local remedy for the complex treatment of the following conditions and diseases: infectious and inflammatory diseases of the oral cavity, oropharynx; infected wounds.

Pharmacological effect

Furasol is an antimicrobial agent, a derivative of nitrofuran. Effective against gram-positive cocci (Staphylococcus spp., Streptococcus spp.), gram-negative bacilli (E. coli, Salmonella spp., Shigella spp., Klebsiella spp.). Resistant: Acinetobacter spp., most strains of Proteus spp., Serratia spp.

The mechanism of action is associated with inhibition of nucleic acid synthesis. Depending on the concentration, it has a bactericidal or bacteriostatic effect.

Against most bacteria, the bacteriostatic concentration is 10–20 μg/ml. The bactericidal concentration is approximately 2 times higher.

Under the influence of nitrofurans in microorganisms, the activity of the respiratory chain and the tricarboxylic acid cycle (Krebs cycle) is suppressed, as well as other biochemical processes are inhibited, which leads to the destruction of their shell or cytoplasmic membrane. Nitrofurans increase complement titer and the ability of leukocytes to phagocytose microorganisms.

Special instructions

The solution is prepared immediately before use.

Do not store the prepared solution.

Active ingredient

Furazidin

Composition

1 sachet of powder for preparing a solution for local and external use contains:

active ingredient:

furazidin potassium 100 mg;

excipients:

sodium chloride – 900 mg.

Contraindications

hypersensitivity to furazidine, other components of the drug or drugs of the nitrofuran series;
allergic dermatitis;
pregnancy;
lactation period;
age up to 4 years.

Side Effects

In some cases, allergic reactions may develop.

In this case, stop using the drug.

Symptomatic therapy is prescribed.

Interaction

In combination with antibiotics it exhibits synergism.

If you drink alcohol during treatment with the drug, the likelihood of developing allergic skin reactions increases.

Overdose

The drug is low toxic.

Cases of overdose have not been described.

Storage conditions

In a dry place, protected from light, at a temperature of 15–25 °C.

Keep out of the reach of children.

Shelf life

4 years.

Manufacturer

Olainfarm, Latvia